Compile Data Set for Download or QSAR
maximum 50k data
Found 19 Enz. Inhib. hit(s) with all data for entry = 50006070
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044312(CHEMBL302780 | Fluoro-(octane-1-sulfonyl)-methanes...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044313(CHEMBL304131 | Chloro-(octane-1-sulfonyl)-methanes...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044311(CHEMBL67511 | TRIFLUOROMETHANE SULFONAMIDE | Trifl...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044309((Octane-1-sulfonyl)-methanesulfonamide | CHEMBL421...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044317((2-Phenyl-ethanesulfonyl)-methanesulfonamide | CHE...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044320((3-Phenyl-propane-1-sulfonyl)-methanesulfonamide |...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044310(CHEMBL68840 | Dichloro-(octane-1-sulfonyl)-methane...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044322((4-Hydroxy-benzenesulfonyl)-methanesulfonamide | C...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044316(CHEMBL66465 | Octylsulfanyl-methanesulfonamide)
Affinity DataIC50:  480nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044319(6-Methoxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-benz...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044314((3-Phenyl-propylsulfanyl)-methanesulfonamide | CHE...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044323(CHEMBL66129 | [2-(2-Methoxy-ethoxy)-ethoxymethanes...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1/2/5B, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of crude dog red blood cell carbonic anhydraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044308(CHEMBL66513 | Phenethylsulfanyl-methanesulfonamide)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044321(1-(Octane-1-sulfonyl)-ethanesulfonic acid amide | ...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044324((4-Hydroxy-phenylsulfanyl)-methanesulfonamide | CH...)
Affinity DataIC50:  2.90E+3nMAssay Description:In vitro inhibition of purified human erythrocyte carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1/2/5B, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044318(CHEMBL305268 | METHANESULFONAMIDE | aminosulfane d...)
Affinity DataIC50:  1.00E+6nMAssay Description:In vitro inhibition of crude dog red blood cell carbonic anhydraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1/2/5B, mitochondrial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044315(CHEMBL69291 | Ethanesulfonic acid amide)
Affinity DataIC50:  1.00E+6nMAssay Description:In vitro inhibition of crude dog red blood cell carbonic anhydraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed