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PubMed code 8691477

Compile data set for download or QSAR
Found 28 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM25400
PNG
((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12
Show InChI InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1
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PubMed
5.90n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM25400
PNG
((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12
Show InChI InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1
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35n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454490
PNG
(CHEMBL2113443)
Show SMILES CNc1nc2c(NC3CCCC3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C16H24N6O4/c1-17-16-21-10-13(20-8-4-2-3-5-8)18-7-19-14(10)22(16)15-12(25)11(24)9(6-23)26-15/h7-9,11-12,15,23-25H,2-6H2,1H3,(H,17,21)(H,18,19,20)/t9-,11-,12-,15-/m1/s1
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260n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Binding affinity for adenosine A1 receptor from rat cortical membrane using [3H]DPCPX without GTP


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454491
PNG
(CHEMBL2113442)
Show SMILES CCNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C17H26N6O4/c1-2-18-14-11-15(20-8-19-14)23(16-13(26)12(25)10(7-24)27-16)17(22-11)21-9-5-3-4-6-9/h8-10,12-13,16,24-26H,2-7H2,1H3,(H,21,22)(H,18,19,20)/t10-,12-,13-,16-/m1/s1
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310n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50410228
PNG
(CHEMBL2113438)
Show SMILES CCCNc1nc2c(NC3CCCC3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C18H28N6O4/c1-2-7-19-18-23-12-15(22-10-5-3-4-6-10)20-9-21-16(12)24(18)17-14(27)13(26)11(8-25)28-17/h9-11,13-14,17,25-27H,2-8H2,1H3,(H,19,23)(H,20,21,22)/t11-,13-,14-,17-/m1/s1
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350n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454494
PNG
(CHEMBL2113439)
Show SMILES CCNc1nc2c(NC3CCCC3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C17H26N6O4/c1-2-18-17-22-11-14(21-9-5-3-4-6-9)19-8-20-15(11)23(17)16-13(26)12(25)10(7-24)27-16/h8-10,12-13,16,24-26H,2-7H2,1H3,(H,18,22)(H,19,20,21)/t10-,12-,13-,16-/m1/s1
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470n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454492
PNG
(CHEMBL2113448)
Show SMILES CCCCNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C19H30N6O4/c1-2-3-8-20-16-13-17(22-10-21-16)25(18-15(28)14(27)12(9-26)29-18)19(24-13)23-11-6-4-5-7-11/h10-12,14-15,18,26-28H,2-9H2,1H3,(H,23,24)(H,20,21,22)/t12-,14-,15-,18-/m1/s1
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760n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454492
PNG
(CHEMBL2113448)
Show SMILES CCCCNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C19H30N6O4/c1-2-3-8-20-16-13-17(22-10-21-16)25(18-15(28)14(27)12(9-26)29-18)19(24-13)23-11-6-4-5-7-11/h10-12,14-15,18,26-28H,2-9H2,1H3,(H,23,24)(H,20,21,22)/t12-,14-,15-,18-/m1/s1
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860n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454490
PNG
(CHEMBL2113443)
Show SMILES CNc1nc2c(NC3CCCC3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C16H24N6O4/c1-17-16-21-10-13(20-8-4-2-3-5-8)18-7-19-14(10)22(16)15-12(25)11(24)9(6-23)26-15/h7-9,11-12,15,23-25H,2-6H2,1H3,(H,17,21)(H,18,19,20)/t9-,11-,12-,15-/m1/s1
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980n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50410228
PNG
(CHEMBL2113438)
Show SMILES CCCNc1nc2c(NC3CCCC3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C18H28N6O4/c1-2-7-19-18-23-12-15(22-10-5-3-4-6-10)20-9-21-16(12)24(18)17-14(27)13(26)11(8-25)28-17/h9-11,13-14,17,25-27H,2-8H2,1H3,(H,19,23)(H,20,21,22)/t11-,13-,14-,17-/m1/s1
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1.05E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454495
PNG
(CHEMBL2113440)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c(NC2CCCC2)nc2c(NC3CCCC3)ncnc12
Show InChI InChI=1S/C20H30N6O4/c27-9-13-15(28)16(29)19(30-13)26-18-14(25-20(26)24-12-7-3-4-8-12)17(21-10-22-18)23-11-5-1-2-6-11/h10-13,15-16,19,27-29H,1-9H2,(H,24,25)(H,21,22,23)/t13-,15-,16-,19-/m1/s1
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1.09E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369216
PNG
(CHEMBL605687)
Show SMILES CCCCNc1nc2c(NC3CCCC3)ncnc2n1C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C19H30N6O4/c1-2-3-8-20-19-24-13-16(23-11-6-4-5-7-11)21-10-22-17(13)25(19)18-15(28)14(27)12(9-26)29-18/h10-12,14-15,18,26-28H,2-9H2,1H3,(H,20,24)(H,21,22,23)/t12-,14-,15-,18?/m1/s1
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1.13E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369216
PNG
(CHEMBL605687)
Show SMILES CCCCNc1nc2c(NC3CCCC3)ncnc2n1C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C19H30N6O4/c1-2-3-8-20-19-24-13-16(23-11-6-4-5-7-11)21-10-22-17(13)25(19)18-15(28)14(27)12(9-26)29-18/h10-12,14-15,18,26-28H,2-9H2,1H3,(H,20,24)(H,21,22,23)/t12-,14-,15-,18?/m1/s1
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1.13E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454491
PNG
(CHEMBL2113442)
Show SMILES CCNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C17H26N6O4/c1-2-18-14-11-15(20-8-19-14)23(16-13(26)12(25)10(7-24)27-16)17(22-11)21-9-5-3-4-6-9/h8-10,12-13,16,24-26H,2-7H2,1H3,(H,21,22)(H,18,19,20)/t10-,12-,13-,16-/m1/s1
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1.26E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454495
PNG
(CHEMBL2113440)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1c(NC2CCCC2)nc2c(NC3CCCC3)ncnc12
Show InChI InChI=1S/C20H30N6O4/c27-9-13-15(28)16(29)19(30-13)26-18-14(25-20(26)24-12-7-3-4-8-12)17(21-10-22-18)23-11-5-1-2-6-11/h10-13,15-16,19,27-29H,1-9H2,(H,24,25)(H,21,22,23)/t13-,15-,16-,19-/m1/s1
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1.28E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454494
PNG
(CHEMBL2113439)
Show SMILES CCNc1nc2c(NC3CCCC3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C17H26N6O4/c1-2-18-17-22-11-14(21-9-5-3-4-6-9)19-8-20-15(11)23(17)16-13(26)12(25)10(7-24)27-16/h8-10,12-13,16,24-26H,2-7H2,1H3,(H,18,22)(H,19,20,21)/t10-,12-,13-,16-/m1/s1
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1.33E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369211
PNG
(CHEMBL604232)
Show SMILES CCCNc1ncnc2n(C3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C18H28N6O4/c1-2-7-19-15-12-16(21-9-20-15)24(17-14(27)13(26)11(8-25)28-17)18(23-12)22-10-5-3-4-6-10/h9-11,13-14,17,25-27H,2-8H2,1H3,(H,22,23)(H,19,20,21)/t11-,13-,14-,17?/m1/s1
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1.59E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369211
PNG
(CHEMBL604232)
Show SMILES CCCNc1ncnc2n(C3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C18H28N6O4/c1-2-7-19-15-12-16(21-9-20-15)24(17-14(27)13(26)11(8-25)28-17)18(23-12)22-10-5-3-4-6-10/h9-11,13-14,17,25-27H,2-8H2,1H3,(H,22,23)(H,19,20,21)/t11-,13-,14-,17?/m1/s1
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1.76E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM32371
PNG
(adenosine-derived inhibitor (Grp78), 3 | adenosine...)
Show SMILES CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H16N6O4/c1-13-11-16-5-8(12)14-3-15-9(5)17(11)10-7(20)6(19)4(2-18)21-10/h3-4,6-7,10,18-20H,2H2,1H3,(H,13,16)(H2,12,14,15)/t4-,6-,7-,10-/m1/s1
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2.42E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454493
PNG
(CHEMBL2113462)
Show SMILES CNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C16H24N6O4/c1-17-13-10-14(19-7-18-13)22(15-12(25)11(24)9(6-23)26-15)16(21-10)20-8-4-2-3-5-8/h7-9,11-12,15,23-25H,2-6H2,1H3,(H,20,21)(H,17,18,19)/t9-,11-,12-,15-/m1/s1
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5.61E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369217
PNG
(CHEMBL603605)
Show SMILES CCCNc1nc2c(N)ncnc2n1C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C13H20N6O4/c1-2-3-15-13-18-7-10(14)16-5-17-11(7)19(13)12-9(22)8(21)6(4-20)23-12/h5-6,8-9,12,20-22H,2-4H2,1H3,(H,15,18)(H2,14,16,17)/t6-,8-,9-,12?/m1/s1
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5.96E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369215
PNG
(CHEMBL604447)
Show SMILES CCNc1nc2c(N)ncnc2n1C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C12H18N6O4/c1-2-14-12-17-6-9(13)15-4-16-10(6)18(12)11-8(21)7(20)5(3-19)22-11/h4-5,7-8,11,19-21H,2-3H2,1H3,(H,14,17)(H2,13,15,16)/t5-,7-,8-,11?/m1/s1
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6.56E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454086
PNG
(CHEMBL2113473)
Show SMILES CCCCNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C14H22N6O4/c1-2-3-4-16-14-19-8-11(15)17-6-18-12(8)20(14)13-10(23)9(22)7(5-21)24-13/h6-7,9-10,13,21-23H,2-5H2,1H3,(H,16,19)(H2,15,17,18)/t7-,9-,10-,13-/m1/s1
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1.14E+4n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (without GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454493
PNG
(CHEMBL2113462)
Show SMILES CNc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NC3CCCC3)nc12
Show InChI InChI=1S/C16H24N6O4/c1-17-13-10-14(19-7-18-13)22(15-12(25)11(24)9(6-23)26-15)16(21-10)20-8-4-2-3-5-8/h7-9,11-12,15,23-25H,2-6H2,1H3,(H,20,21)(H,17,18,19)/t9-,11-,12-,15-/m1/s1
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1.57E+4n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM32371
PNG
(adenosine-derived inhibitor (Grp78), 3 | adenosine...)
Show SMILES CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H16N6O4/c1-13-11-16-5-8(12)14-3-15-9(5)17(11)10-7(20)6(19)4(2-18)21-10/h3-4,6-7,10,18-20H,2H2,1H3,(H,13,16)(H2,12,14,15)/t4-,6-,7-,10-/m1/s1
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1.86E+4n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369215
PNG
(CHEMBL604447)
Show SMILES CCNc1nc2c(N)ncnc2n1C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C12H18N6O4/c1-2-14-12-17-6-9(13)15-4-16-10(6)18(12)11-8(21)7(20)5(3-19)22-11/h4-5,7-8,11,19-21H,2-3H2,1H3,(H,14,17)(H2,13,15,16)/t5-,7-,8-,11?/m1/s1
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2.38E+4n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50369217
PNG
(CHEMBL603605)
Show SMILES CCCNc1nc2c(N)ncnc2n1C1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C13H20N6O4/c1-2-3-15-13-18-7-10(14)16-5-17-11(7)19(13)12-9(22)8(21)6(4-20)23-12/h5-6,8-9,12,20-22H,2-4H2,1H3,(H,15,18)(H2,14,16,17)/t6-,8-,9-,12?/m1/s1
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3.47E+4n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50454086
PNG
(CHEMBL2113473)
Show SMILES CCCCNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C14H22N6O4/c1-2-3-4-16-14-19-8-11(15)17-6-18-12(8)20(14)13-10(23)9(22)7(5-21)24-13/h6-7,9-10,13,21-23H,2-5H2,1H3,(H,16,19)(H2,15,17,18)/t7-,9-,10-,13-/m1/s1
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4.55E+4n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Displacement of [3H]DPCPX (with GTP) from Adenosine A1 receptor of rat cortical membrane


J Med Chem 39: 1463-71 (1996)


Article DOI: 10.1021/jm950267m
BindingDB Entry DOI: 10.7270/Q2WH2QNT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%