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Found 21 Enz. Inhib. hit(s) with all data for entry = 50006876
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054838(3-(4-Tridec-2-ynyloxymethyl-phenyl)-propionic acid...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054833(3-{4-[((E)-Tridec-2-enyl)oxymethyl]-phenyl}-propio...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054836((4-Tridec-2-ynyloxymethyl-phenyl)-acetic acid | CH...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054851(4-Tridec-2-ynyloxymethyl-benzoic acid | CHEMBL1422...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054840(3-(4-Undec-2-ynyloxymethyl-phenyl)-propionic acid ...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054844(3-(4-Tetradeca-2,3-dienyloxymethyl-phenyl)-propion...)
Affinity DataIC50:  280nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054846(3-(4-Pentadec-2-ynyloxymethyl-phenyl)-propionic ac...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054832(3-(3-Tridec-2-ynyloxymethyl-phenyl)-propionic acid...)
Affinity DataIC50:  320nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054849(3-(4-Non-2-ynyloxymethyl-phenyl)-propionic acid | ...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054850(3-{4-[((Z)-Tridec-2-enyl)oxymethyl]-phenyl}-propio...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50407987(CHEMBL2112001)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054841(3-[4-(7-Phenyl-hept-2-ynyloxymethyl)-phenyl]-propi...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054835(4-Dec-2-ynyloxymethyl-benzoic acid | CHEMBL359394)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054845(4-(4-Tridec-2-ynyloxymethyl-phenyl)-butyric acid |...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054842(3-(3-Non-2-ynyloxymethyl-phenyl)-propionic acid | ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054834(3-(4-Tridecyloxymethyl-phenyl)-propionic acid | CH...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054843(3-(3-Undec-2-ynylsulfanylmethyl-phenyl)-propionic ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054847(4-Heptadec-2-ynyloxymethyl-benzoic acid | CHEMBL14...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054839(3-(4-Heptadec-2-ynyloxymethyl-phenyl)-propionic ac...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054848(3-(3-Non-3-ynyloxymethyl-phenyl)-propionic acid | ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Sus scrofa)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50054837(3-(3-Undec-2-ynyloxymethyl-phenyl)-propionic acid ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed