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Found 14 Enz. Inhib. hit(s) with all data for entry = 50007457
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063544(1-(6-(methylthio)naphthalen-2-yl)propan-2-amine | ...)
Affinity DataIC50:  74nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50003582((R-PIA)2-(4-Iodo-phenyl)-1-methyl-ethylamine | 2-(...)
Affinity DataIC50:  82nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50042722(2-Indan-5-yl-1-methyl-ethylamine | CHEMBL6842)
Affinity DataIC50:  82nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063547(1-Methyl-2-(4-methyl-benzo[1,3]dioxol-5-yl)-ethyla...)
Affinity DataIC50:  93nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063546(1-Methyl-2-(7-methyl-benzo[1,3]dioxol-5-yl)-ethyla...)
Affinity DataIC50:  107nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  266nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)
Affinity DataIC50:  478nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063545(1-Methyl-2-(6-methyl-benzo[1,3]dioxol-5-yl)-ethyla...)
Affinity DataIC50:  783nMAssay Description:Activity towards Serotonin transporter was determined by the ability to inhibit [3H]-5-HT uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50042722(2-Indan-5-yl-1-methyl-ethylamine | CHEMBL6842)
Affinity DataIC50:  849nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50003582((R-PIA)2-(4-Iodo-phenyl)-1-methyl-ethylamine | 2-(...)
Affinity DataIC50:  993nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063546(1-Methyl-2-(7-methyl-benzo[1,3]dioxol-5-yl)-ethyla...)
Affinity DataIC50:  1.49E+3nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063547(1-Methyl-2-(4-methyl-benzo[1,3]dioxol-5-yl)-ethyla...)
Affinity DataIC50:  1.94E+3nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063544(1-(6-(methylthio)naphthalen-2-yl)propan-2-amine | ...)
Affinity DataIC50:  2.38E+3nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50063545(1-Methyl-2-(6-methyl-benzo[1,3]dioxol-5-yl)-ethyla...)
Affinity DataIC50:  4.60E+3nMAssay Description:Compound was tested for the ability to inhibit [3H]-norepinephrine binding to Norepinephrine transporter in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed