Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50007626
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065518(4-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-4-o-t...)
Affinity DataIC50:  8nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065539((E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  80nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065533((E)-3-[2-Cyano-5-(pyridin-3-ylmethoxy)-phenyl]-2-p...)
Affinity DataIC50:  150nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065548((E)-2-(2-Chloro-phenyl)-3-[2-cyano-5-(thiophen-3-y...)
Affinity DataIC50:  200nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065545((E)-2-Benzo[1,3]dioxol-5-yl-3-[2-cyano-5-(thiophen...)
Affinity DataIC50:  200nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065543(2-((E)-3-Hydroxy-2-o-tolyl-propenyl)-4-(thiophen-3...)
Affinity DataIC50:  300nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065544((E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  300nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065537((E)-2-(2-Chloro-phenyl)-3-[2-nitro-5-(thiophen-3-y...)
Affinity DataIC50:  400nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065528((E)-3-[2-Nitro-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  500nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065531((E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  600nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065550((E)-2-(2-Fluoro-phenyl)-3-[2-nitro-5-(thiophen-3-y...)
Affinity DataIC50:  600nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065540((E)-3-(5-Benzyloxy-2-nitro-phenyl)-2-phenyl-acryli...)
Affinity DataIC50:  600nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065549((Z)-5-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-4-...)
Affinity DataIC50:  700nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065529((E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  700nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065538(2-((E)-3-Hydroxy-2-phenyl-propenyl)-4-(thiophen-3-...)
Affinity DataIC50:  800nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065536((E)-3-(5-Benzyloxy-2-nitro-phenyl)-2-(2-fluoro-phe...)
Affinity DataIC50:  900nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065541(5-(3-Benzyloxy-phenyl)-5-oxo-4-phenyl-pentanoic ac...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065535((E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065532((E)-3-[5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-ph...)
Affinity DataIC50:  1.30E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065547((E)-2-(2-Chloro-phenyl)-3-[2-nitro-5-(thiophen-3-y...)
Affinity DataIC50:  1.30E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065542((E)-3-[2-Nitro-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065551(4-(3-Benzyloxy-phenoxy)-4-phenyl-butyric acid | CH...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065526((E)-2-(2-Chloro-6-fluoro-phenyl)-3-[2-nitro-5-(thi...)
Affinity DataIC50:  2.00E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065527((E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065534((E)-3-[2-Bromo-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065530((E)-3-[2-Cyano-5-(thiophen-3-ylmethoxy)-phenyl]-2-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065552((Z)-5-(3-Benzyloxy-phenyl)-4-phenyl-pent-4-enoic a...)
Affinity DataIC50:  5.30E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065553((E)-3-(3-Benzyloxy-phenyl)-2-phenyl-acrylic acid |...)
Affinity DataIC50:  6.00E+3nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065546((E)-3-(3-Benzyloxy-phenyl)-2-phenyl-prop-2-en-1-ol...)
Affinity DataIC50:  2.00E+4nMAssay Description:Concentration required to inhibit 50% Et-1 binding to endothelin A receptor in rat A-10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed