Compile Data Set for Download or QSAR
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Found 39 Enz. Inhib. hit(s) with all data for entry = 6164
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112737(US8629141, 4)
Affinity DataKi:  1nM IC50:  15.6nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112736(US8629141, 2)
Affinity DataIC50:  41.8nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112754(US8629141, 21)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112771(US8629141, 41)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112770(US8629141, 40)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112769(US8629141, 39)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112768(US8629141, 38)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112767(US8629141, 37)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112766(US8629141, 36)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112763(US8629141, 33)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112762(US8629141, 32)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112761(US8629141, 31)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112759(US8629141, 29)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112758(US8629141, 28)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112757(US8629141, 27)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112755(US8629141, 25)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112773(US8629141, 43)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112753(US8629141, 20)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112748(US8629141, 15)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112742(US8629141, 9)
Affinity DataIC50: <100nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112735(US8629141, 1)
Affinity DataIC50:  201nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112760(US8629141, 30)
Affinity DataIC50: <500nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112756(US8629141, 26)
Affinity DataIC50: <500nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112740(US8629141, 7)
Affinity DataIC50: <1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112739(US8629141, 6)
Affinity DataIC50: <1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112752(US8629141, 19)
Affinity DataIC50: >1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112772(US8629141, 42)
Affinity DataIC50: <1.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112743(US8629141, 10)
Affinity DataIC50: <5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112744(US8629141, 11)
Affinity DataIC50: <5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112745(US8629141, 12)
Affinity DataIC50: <5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112750(US8629141, 17)
Affinity DataIC50: >5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112751(US8629141, 18)
Affinity DataIC50: >5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112741(US8629141, 8)
Affinity DataIC50: <5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112749(US8629141, 16)
Affinity DataIC50: >5.00E+3nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112738(US8629141, 5)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112747(US8629141, 14)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112764(US8629141, 34)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112765(US8629141, 35)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM112746(US8629141, 13)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent