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Found 13 Enz. Inhib. hit(s) with all data for entry = 7976
TargetHistamine H4 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM227453(US9333199, S-NORKETOTIFEN (SNORK))
Affinity DataKi:  1.10E+3nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM181150(US9138431, R-NORKETOTIFEN (RNORK) | US9138431, RS-...)
Affinity DataKi:  2.00E+3nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM227454(US9333199, R-NORKETOTIFEN (RNORK))
Affinity DataKi:  2.30E+3nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM50017674((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...)
Affinity DataKi:  1.10E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM50073179(8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-be...)
Affinity DataKi:  1.60E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H4 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM94597((Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene...)
Affinity DataKi:  2.10E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM94597((Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene...)
Affinity DataIC50:  2.30E+3nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM181150(US9138431, R-NORKETOTIFEN (RNORK) | US9138431, RS-...)
Affinity DataIC50:  1.10E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM50073179(8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-be...)
Affinity DataIC50:  1.60E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM227454(US9333199, R-NORKETOTIFEN (RNORK))
Affinity DataIC50:  1.70E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM227453(US9333199, S-NORKETOTIFEN (SNORK))
Affinity DataIC50:  2.30E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM50017674((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...)
Affinity DataIC50:  8.40E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
Bridge Pharma

US Patent
LigandPNGBDBM22876(CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...)
Affinity DataIC50:  1.50E+6nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank