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Found 32 Enz. Inhib. hit(s) with all data for entry = 50008638
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  6nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075609((E)-(S)-4-((2R,5S)-2-Benzyl-5-benzylsulfanylcarbon...)
Affinity DataEC50:  680nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  500nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  180nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  1.40E+3nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  170nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  360nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075602((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  100nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  20nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  100nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  50nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  60nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065606((E)-(S)-4-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-m...)
Affinity DataEC50:  540nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075602((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  20nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  160nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075605((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  190nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  280nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  1.00E+3nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075606((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  430nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075604((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  130nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  600nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075599((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  560nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  180nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075600((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  130nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated, virus infected cells to 50...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075601((E)-(S)-4-((2R,5S)-2-Benzyl-5-benzyloxycarbonylami...)
Affinity DataEC50:  360nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075607((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  1.60E+3nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075602((E)-(S)-4-((2R,5S)-2-Benzyl-5-cyclopentylsulfanylc...)
Affinity DataEC50:  35nMAssay Description:The EC50 was calculated as the concentration of drug that increased the percentage of formazan production in drug treated,virus infected cells to 50%...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075608((E)-(S)-4-((2R,5S)-2-Benzyl-5-benzylsulfanylcarbon...)
Affinity DataEC50:  190nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075603((E)-(S)-6-Carbamoyl-4-[(2R,5S)-5-cyclopentylsulfan...)
Affinity DataEC50:  50nMAssay Description:Increased percentage of formazan production in drug treated virus infected cells to equal 50% of control drug free uninfected cells on serotype 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed