Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50008783
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077089(4-[(S)-((2S,5R)-4-Benzo[1,3]dioxol-5-ylmethyl-2,5-...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077083(4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077085(CHEMBL27432 | N,N-Diethyl-4-{phenyl-[4-(1,2,3,4-te...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50039029((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Affinity DataIC50:  2nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077081(CHEMBL27779 | N,N-Diethyl-4-{[4-(2-hydroxy-ethyl)-...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077086(4-[(4-Cyclopentyl-piperazin-1-yl)-phenyl-methyl]-N...)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  8nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077091(CHEMBL416930 | N,N-Diethyl-4-{[4-(4-hydroxy-phenyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077082(CHEMBL150430 | CHEMBL27944 | N,N-Diethyl-4-[phenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077093(4-[(4-Allyl-[1,4]diazepan-1-yl)-phenyl-methyl]-N,N...)
Affinity DataIC50:  13nMAssay Description:Compound was tested for inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077088(CHEMBL27579 | N,N-Diethyl-4-[(octahydro-quinoxalin...)
Affinity DataIC50:  29nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077090(4-[(3,5-Dimethyl-piperazin-1-yl)-phenyl-methyl]-N,...)
Affinity DataIC50:  42nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077084(4-{[Benzyl-(2-dimethylamino-ethyl)-amino]-phenyl-m...)
Affinity DataIC50:  70nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077087(4-[(2-Amino-2-methyl-propylamino)-phenyl-methyl]-N...)
Affinity DataIC50:  120nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077084(4-{[Benzyl-(2-dimethylamino-ethyl)-amino]-phenyl-m...)
Affinity DataIC50:  483nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]- U-69,593 (1.5 nM) as radioligand in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077089(4-[(S)-((2S,5R)-4-Benzo[1,3]dioxol-5-ylmethyl-2,5-...)
Affinity DataIC50:  702nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077092(4-{[(2-Dimethylamino-ethyl)-ethyl-amino]-phenyl-me...)
Affinity DataIC50:  845nMAssay Description:Inhibition of binding of [3H]- -naltrindole (0.15 nM) to membranes from CHO cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50:  1.99E+3nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]- U-69,593 (1.5 nM) as radioligand in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077083(4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]- U-69,593 (1.5 nM) as radioligand in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50039029((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Affinity DataIC50:  4.10E+3nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]- U-69,593 (1.5 nM) as radioligand in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50039029((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Affinity DataIC50:  4.80E+3nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077085(CHEMBL27432 | N,N-Diethyl-4-{phenyl-[4-(1,2,3,4-te...)
Affinity DataIC50:  6.24E+3nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077091(CHEMBL416930 | N,N-Diethyl-4-{[4-(4-hydroxy-phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077081(CHEMBL27779 | N,N-Diethyl-4-{[4-(2-hydroxy-ethyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077083(4-[(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077084(4-{[Benzyl-(2-dimethylamino-ethyl)-amino]-phenyl-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077082(CHEMBL150430 | CHEMBL27944 | N,N-Diethyl-4-[phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50: >5.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50077066(4-[(4-Allyl-piperazin-1-yl)-phenyl-methyl]-N,N-die...)
Affinity DataIC50: >5.00E+4nMAssay Description:Binding affinity towards mu opioid receptor using [3H]- -DAMGO (1.5 nM) as radioligand in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed