Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50011004
TargetCathepsin G(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50:  0.390nMAssay Description:Compound was evaluated for its inhibitory activity against human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50:  0.690nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101136(1,3-Bis-benzo[1,3]dioxol-5-ylmethyl-[1,3]diazetidi...)
Affinity DataIC50:  0.850nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101135(1,3-Bis-(4-methoxy-benzyl)-[1,3]diazetidine-2,4-di...)
Affinity DataIC50:  2nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101131(1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL...)
Affinity DataIC50:  2.30nMAssay Description:Compound was evaluated for its inhibitory activity against human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101137(1,3-Bis-(3-methoxy-benzyl)-[1,3]diazetidine-2,4-di...)
Affinity DataIC50:  2.30nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101131(1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL...)
Affinity DataIC50:  2.40nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50:  4nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50:  39nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101134(1,3-Bis-benzo[1,3]dioxol-5-yl-[1,3]diazetidine-2,4...)
Affinity DataIC50:  48nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101133(1,3-Diethyl-[1,3]diazetidine-2,4-dione | CHEMBL298...)
Affinity DataIC50:  58nMAssay Description:Compound was evaluated for its inhibitory activity against human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50:  72nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for its inhibitory activity against human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101131(1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL...)
Affinity DataIC50:  140nMAssay Description:Compound was evaluated for its inhibitory activity against human Serine protease chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101131(1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL...)
Affinity DataIC50:  200nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101131(1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL...)
Affinity DataIC50:  230nMAssay Description:Compound was evaluated for its inhibitory activity against human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101133(1,3-Diethyl-[1,3]diazetidine-2,4-dione | CHEMBL298...)
Affinity DataIC50:  740nMAssay Description:Compound was evaluated for its inhibitory activity against human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101133(1,3-Diethyl-[1,3]diazetidine-2,4-dione | CHEMBL298...)
Affinity DataIC50:  740nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101131(1,3-Di-p-tolyl-[1,3]diazetidine-2,4-dione | CHEMBL...)
Affinity DataIC50:  2.30E+3nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101132(1,3-Dibenzyl-[1,3]diazetidine-2,4-dione | CHEMBL47...)
Affinity DataIC50:  2.90E+3nMAssay Description:Compound was evaluated for its inhibitory activity against human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101133(1,3-Diethyl-[1,3]diazetidine-2,4-dione | CHEMBL298...)
Affinity DataIC50:  5.60E+3nMAssay Description:Compound was evaluated for its inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101133(1,3-Diethyl-[1,3]diazetidine-2,4-dione | CHEMBL298...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50101133(1,3-Diethyl-[1,3]diazetidine-2,4-dione | CHEMBL298...)
Affinity DataIC50:  3.90E+4nMAssay Description:Compound was evaluated for its inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed