Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50036066
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.0300nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50221416(22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...)
Affinity DataKi:  0.700nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  3.80nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001674(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataKi:  5.30nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001675(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataKi:  11nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001679(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi:  11nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi:  22nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006946(2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKi:  35nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001678(22-[3-phenyl-(E)-2-propenyl]-14-oxa-11,22-diazahep...)
Affinity DataKi:  106nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi:  173nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  332nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001674(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataKi:  375nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50221416(22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...)
Affinity DataKi:  468nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001674(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataKi:  935nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001678(22-[3-phenyl-(E)-2-propenyl]-14-oxa-11,22-diazahep...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001678(22-[3-phenyl-(E)-2-propenyl]-14-oxa-11,22-diazahep...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001675(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001675(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor mu 1 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006946(2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001679(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001679(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50006946(2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataKi:  2.62E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50221416(22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...)
Affinity DataKi:  4.47E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  2.80nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deference.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001674(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataIC50:  85nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001675(14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04...)
Affinity DataIC50:  124nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001679(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataIC50:  171nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50001677(22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.0...)
Affinity DataIC50:  179nMAssay Description:Compound was tested for agonistic activity against the opioid receptor in electrically stimulated mouse vas deferenceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed