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Found 28 Enz. Inhib. hit(s) with all data for entry = 50037395
TargetAdenosine receptor A2b(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166735(3-[5-(2-Methyl-imidazol-1-yl)-2-(pyrazin-2-ylamino...)
Affinity DataKi:  10nMAssay Description:Inhibition of luciferase production elicited by NECA by compound in CHO cells transfected with human adenosine A2b receptor and a luciferase expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166742(3-[2-(3-Methyl-pyridin-2-ylamino)-5-[1,2,4]triazol...)
Affinity DataKi:  20nMAssay Description:Inhibition of luciferase production elicited by NECA by compound in CHO cells transfected with human adenosine A2b receptor and a luciferase expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166739(3-[2-(Pyridin-2-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166742(3-[2-(3-Methyl-pyridin-2-ylamino)-5-[1,2,4]triazol...)
Affinity DataKi:  37nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166739(3-[2-(Pyridin-2-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  53nMAssay Description:Inhibition of luciferase production elicited by NECA by compound in CHO cells transfected with human adenosine A2b receptor and a luciferase expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166745(3-[2-(Pyridin-4-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  62nMAssay Description:Inhibition of luciferase production elicited by NECA by compound in CHO cells transfected with human adenosine A2b receptor and a luciferase expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166737(3-[2-(Pyridin-3-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  86nMAssay Description:Inhibition of luciferase production elicited by NECA by compound in CHO cells transfected with human adenosine A2b receptor and a luciferase expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166743(3-[5-Imidazol-1-yl-2-(pyridin-3-ylamino)-thiazol-4...)
Affinity DataKi:  92nMAssay Description:Inhibition of luciferase production elicited by NECA by compound in CHO cells transfected with human adenosine A2b receptor and a luciferase expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166743(3-[5-Imidazol-1-yl-2-(pyridin-3-ylamino)-thiazol-4...)
Affinity DataKi:  124nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166741(4-(3-cyanophenyl)-5-(1H-1,2,4-triazol-1-yl)-1,3-th...)
Affinity DataKi:  134nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166735(3-[5-(2-Methyl-imidazol-1-yl)-2-(pyrazin-2-ylamino...)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]ZM-241,385 from human adenosine A2a receptors transfected in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166735(3-[5-(2-Methyl-imidazol-1-yl)-2-(pyrazin-2-ylamino...)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166745(3-[2-(Pyridin-4-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  304nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166741(4-(3-cyanophenyl)-5-(1H-1,2,4-triazol-1-yl)-1,3-th...)
Affinity DataKi:  365nMAssay Description:Inhibition of luciferase production elicited by NECA by compound in CHO cells transfected with human adenosine A2b receptor and a luciferase expressi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166735(3-[5-(2-Methyl-imidazol-1-yl)-2-(pyrazin-2-ylamino...)
Affinity DataKi:  419nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166743(3-[5-Imidazol-1-yl-2-(pyridin-3-ylamino)-thiazol-4...)
Affinity DataKi:  560nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166737(3-[2-(Pyridin-3-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  698nMAssay Description:Displacement of [125I]-AB-MECA from human adenosine A3 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166737(3-[2-(Pyridin-3-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  1.53E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166739(3-[2-(Pyridin-2-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  1.76E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166739(3-[2-(Pyridin-2-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of [3H]ZM-241,385 from human adenosine A2a receptors transfected in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166737(3-[2-(Pyridin-3-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [3H]ZM-241,385 from human adenosine A2a receptors transfected in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166743(3-[5-Imidazol-1-yl-2-(pyridin-3-ylamino)-thiazol-4...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]ZM-241,385 from human adenosine A2a receptors transfected in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166741(4-(3-cyanophenyl)-5-(1H-1,2,4-triazol-1-yl)-1,3-th...)
Affinity DataKi:  2.84E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166745(3-[2-(Pyridin-4-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  3.78E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166745(3-[2-(Pyridin-4-ylamino)-5-[1,2,4]triazol-1-yl-thi...)
Affinity DataKi:  4.16E+3nMAssay Description:Displacement of [3H]ZM-241,385 from human adenosine A2a receptors transfected in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166741(4-(3-cyanophenyl)-5-(1H-1,2,4-triazol-1-yl)-1,3-th...)
Affinity DataKi:  5.61E+3nMAssay Description:Displacement of [3H]ZM-241,385 from human adenosine A2a receptors transfected in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166742(3-[2-(3-Methyl-pyridin-2-ylamino)-5-[1,2,4]triazol...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]ZM-241,385 from human adenosine A2a receptors transfected in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50166742(3-[2-(3-Methyl-pyridin-2-ylamino)-5-[1,2,4]triazol...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptors transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed