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PubMed code 15950465

Compile data set for download or QSAR
Found 31 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168577
PNG
(4-(1-Cyclopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-fu...)
Show SMILES Nc1nonc1-c1nc2cnccc2n1C1CC1
Show InChI InChI=1S/C11H10N6O/c12-10-9(15-18-16-10)11-14-7-5-13-4-3-8(7)17(11)6-1-2-6/h3-6H,1-2H2,(H2,12,16)
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n/an/a 1.80n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168587
PNG
(4-(1-Cyclohexyl-1H-imidazo[4,5-c]pyridin-2-yl)-fur...)
Show SMILES Nc1nonc1-c1nc2cnccc2n1C1CCCCC1
Show InChI InChI=1S/C14H16N6O/c15-13-12(18-21-19-13)14-17-10-8-16-7-6-11(10)20(14)9-4-2-1-3-5-9/h6-9H,1-5H2,(H2,15,19)
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n/an/a 3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM14032
PNG
(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)
Show SMILES CCn1c(nc2cnccc12)-c1nonc1N
Show InChI InChI=1S/C10H10N6O/c1-2-16-7-3-4-12-5-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3,(H2,11,15)
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n/an/a 3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168581
PNG
(4-(1-Phenyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)
Show SMILES Nc1nonc1-c1nc2cnccc2n1-c1ccccc1
Show InChI InChI=1S/C14H10N6O/c15-13-12(18-21-19-13)14-17-10-8-16-7-6-11(10)20(14)9-4-2-1-3-5-9/h1-8H,(H2,15,19)
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n/an/a 11n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168578
PNG
(4-[1-(1-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl...)
Show SMILES CCCC(N)n1c(nc2cnccc12)-c1nonc1N
Show InChI InChI=1/C12H15N7O/c1-2-3-9(13)19-8-4-5-15-6-7(8)16-12(19)10-11(14)18-20-17-10/h4-6,9H,2-3,13H2,1H3,(H2,14,18)
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168601
PNG
(4-(1-Piperidin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)...)
Show SMILES Nc1nonc1-c1nc2cnccc2n1C1CCNCC1
Show InChI InChI=1S/C13H15N7O/c14-12-11(18-21-19-12)13-17-9-7-16-6-3-10(9)20(13)8-1-4-15-5-2-8/h3,6-8,15H,1-2,4-5H2,(H2,14,19)
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n/an/a 17n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168594
PNG
(2-(4-Amino-furazan-3-yl)-1-ethyl-1H-benzoimidazol-...)
Show SMILES CCn1c(nc2cc(O)ccc12)-c1nonc1N
Show InChI InChI=1S/C11H11N5O2/c1-2-16-8-4-3-6(17)5-7(8)13-11(16)9-10(12)15-18-14-9/h3-5,17H,2H2,1H3,(H2,12,15)
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n/an/a 17n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168576
PNG
(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyrazin-...)
Show SMILES CCn1c(nc2cnccc12)-c1nccnc1N
Show InChI InChI=1S/C12H12N6/c1-2-18-9-3-4-14-7-8(9)17-12(18)10-11(13)16-6-5-15-10/h3-7H,2H2,1H3,(H2,13,16)
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n/an/a 20n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168595
PNG
(4-(1-Ethyl-5-fluoro-1H-benzoimidazol-2-yl)-furazan...)
Show SMILES CCn1c(nc2cc(F)ccc12)-c1nonc1N
Show InChI InChI=1S/C11H10FN5O/c1-2-17-8-4-3-6(12)5-7(8)14-11(17)9-10(13)16-18-15-9/h3-5H,2H2,1H3,(H2,13,16)
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n/an/a 38n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168586
PNG
(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-5-methyl...)
Show SMILES CCn1c(nc2cnccc12)-c1c(C)[nH]nc1N
Show InChI InChI=1S/C12H14N6/c1-3-18-9-4-5-14-6-8(9)15-12(18)10-7(2)16-17-11(10)13/h4-6H,3H2,1-2H3,(H3,13,16,17)
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n/an/a 55n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168589
PNG
(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)
Show SMILES CCn1c(nc2cnccc12)-c1cccnc1N
Show InChI InChI=1S/C13H13N5/c1-2-18-11-5-7-15-8-10(11)17-13(18)9-4-3-6-16-12(9)14/h3-8H,2H2,1H3,(H2,14,16)
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n/an/a 107n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168582
PNG
(4-(1-Methyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)
Show SMILES Cn1c(nc2cnccc12)-c1nonc1N
Show InChI InChI=1S/C9H8N6O/c1-15-6-2-3-11-4-5(6)12-9(15)7-8(10)14-16-13-7/h2-4H,1H3,(H2,10,14)
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n/an/a 126n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168588
PNG
(4-(1-Ethyl-1H-benzoimidazol-2-yl)-furazan-3-ylamin...)
Show SMILES CCn1c(nc2ccccc12)-c1nonc1N
Show InChI InChI=1S/C11H11N5O/c1-2-16-8-6-4-3-5-7(8)13-11(16)9-10(12)15-17-14-9/h3-6H,2H2,1H3,(H2,12,15)
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n/an/a 140n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168593
PNG
(2-(4-Amino-furazan-3-yl)-3-ethyl-3H-benzoimidazol-...)
Show SMILES CCn1c(nc2ccc(O)cc12)-c1nonc1N
Show InChI InChI=1S/C11H11N5O2/c1-2-16-8-5-6(17)3-4-7(8)13-11(16)9-10(12)15-18-14-9/h3-5,17H,2H2,1H3,(H2,12,15)
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n/an/a 258n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168598
PNG
(CHEMBL185731 | [2-(4-Amino-furazan-3-yl)-1-ethyl-1...)
Show SMILES CCn1c(nc2cc(CO)ccc12)-c1nonc1N
Show InChI InChI=1S/C12H13N5O2/c1-2-17-9-4-3-7(6-18)5-8(9)14-12(17)10-11(13)16-19-15-10/h3-5,18H,2,6H2,1H3,(H2,13,16)
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n/an/a 974n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168592
PNG
(4-(1-Ethyl-5-methoxy-1H-benzoimidazol-2-yl)-furaza...)
Show SMILES CCn1c(nc2cc(OC)ccc12)-c1nonc1N
Show InChI InChI=1S/C12H13N5O2/c1-3-17-9-5-4-7(18-2)6-8(9)14-12(17)10-11(13)16-19-15-10/h4-6H,3H2,1-2H3,(H2,13,16)
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n/an/a 1.20E+3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168599
PNG
(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,5-dime...)
Show SMILES CCn1c(nc2cnccc12)-c1c(N)nn(C)c1C
Show InChI InChI=1S/C13H16N6/c1-4-19-10-5-6-15-7-9(10)16-13(19)11-8(2)18(3)17-12(11)14/h5-7H,4H2,1-3H3,(H2,14,17)
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n/an/a 1.52E+3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168584
PNG
(4-(3-Ethyl-3H-imidazo[4,5-c]pyridin-2-yl)-furazan-...)
Show SMILES CCn1c(nc2ccncc12)-c1nonc1N
Show InChI InChI=1S/C10H10N6O/c1-2-16-7-5-12-4-3-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3,(H2,11,15)
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n/an/a 1.54E+3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168600
PNG
(4-(1H-Imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamin...)
Show SMILES Nc1nonc1-c1nc2ccncc2[nH]1
Show InChI InChI=1S/C8H6N6O/c9-7-6(13-15-14-7)8-11-4-1-2-10-3-5(4)12-8/h1-3H,(H2,9,14)(H,11,12)
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n/an/a 1.96E+3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168591
PNG
(4-(1-Ethyl-6-fluoro-1H-benzoimidazol-2-yl)-furazan...)
Show SMILES CCn1c(nc2ccc(F)cc12)-c1nonc1N
Show InChI InChI=1S/C11H10FN5O/c1-2-17-8-5-6(12)3-4-7(8)14-11(17)9-10(13)16-18-15-9/h3-5H,2H2,1H3,(H2,13,16)
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n/an/a 2.12E+3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168583
PNG
(1-[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-benzoimidaz...)
Show SMILES CCn1c(nc2cc(ccc12)C(C)=O)-c1nonc1N
Show InChI InChI=1S/C13H13N5O2/c1-3-18-10-5-4-8(7(2)19)6-9(10)15-13(18)11-12(14)17-20-16-11/h4-6H,3H2,1-2H3,(H2,14,17)
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n/an/a 4.39E+3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168585
PNG
(CHEMBL362494 | N-[4-(1-Ethyl-1H-imidazo[4,5-c]pyri...)
Show SMILES CCn1c(nc2cnccc12)-c1nonc1NC(C)=O
Show InChI InChI=1S/C12H12N6O2/c1-3-18-9-4-5-13-6-8(9)15-12(18)10-11(14-7(2)19)17-20-16-10/h4-6H,3H2,1-2H3,(H,14,17,19)
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n/an/a 5.10E+3n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168575
PNG
(1-Ethyl-2-pyridin-3-yl-1H-imidazo[4,5-c]pyridine |...)
Show SMILES CCn1c(nc2cnccc12)-c1cccnc1
Show InChI InChI=1S/C13H12N4/c1-2-17-12-5-7-15-9-11(12)16-13(17)10-4-3-6-14-8-10/h3-9H,2H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168602
PNG
(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-5-methyl...)
Show SMILES CCn1c(nc2cnccc12)-c1c(C)onc1N
Show InChI InChI=1S/C12H13N5O/c1-3-17-9-4-5-14-6-8(9)15-12(17)10-7(2)18-16-11(10)13/h4-6H,3H2,1-2H3,(H2,13,16)
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168579
PNG
(5-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)
Show SMILES CCn1c(nc2cnccc12)-c1ccc(N)nc1
Show InChI InChI=1S/C13H13N5/c1-2-18-11-5-6-15-8-10(11)17-13(18)9-3-4-12(14)16-7-9/h3-8H,2H2,1H3,(H2,14,16)
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168597
PNG
(2-(1,2-Dihydro-pyridin-4-yl)-1-ethyl-1H-imidazo[4,...)
Show SMILES CCn1c(nc2cnccc12)C1=CC=NCC1
Show InChI InChI=1S/C13H14N4/c1-2-17-12-5-8-15-9-11(12)16-13(17)10-3-6-14-7-4-10/h3,5-6,8-9H,2,4,7H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168590
PNG
(2-(4-Chloro-furazan-3-yl)-1-ethyl-1H-imidazo[4,5-c...)
Show SMILES CCn1c(nc2cnccc12)-c1nonc1Cl
Show InChI InChI=1S/C10H8ClN5O/c1-2-16-7-3-4-12-5-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168574
PNG
(1-Ethyl-2-furan-3-yl-1H-imidazo[4,5-c]pyridine | C...)
Show SMILES CCn1c(nc2cnccc12)-c1ccoc1
Show InChI InChI=1S/C12H11N3O/c1-2-15-11-3-5-13-7-10(11)14-12(15)9-4-6-16-8-9/h3-8H,2H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168573
PNG
(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)
Show SMILES CCn1c(nc2cnccc12)-c1ccc[nH]c1=O
Show InChI InChI=1S/C13H12N4O/c1-2-17-11-5-7-14-8-10(11)16-12(17)9-4-3-6-15-13(9)18/h3-8H,2H2,1H3,(H,15,18)
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168580
PNG
(2-(1,2-Dihydro-pyridin-2-yl)-1-ethyl-1H-imidazo[4,...)
Show SMILES CCn1c(nc2cnccc12)C1C=CCC=N1
Show InChI InChI=1/C13H14N4/c1-2-17-12-6-8-14-9-11(12)16-13(17)10-5-3-4-7-15-10/h3,5-10H,2,4H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168596
PNG
(1-Ethyl-2-phenyl-1H-imidazo[4,5-c]pyridine | CHEMB...)
Show SMILES CCn1c(nc2cnccc12)-c1ccccc1
Show InChI InChI=1S/C14H13N3/c1-2-17-13-8-9-15-10-12(13)16-14(17)11-6-4-3-5-7-11/h3-10H,2H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%