BindingDB PrimarySearch

Found 27 Enz. Inhib. hit(s) with all data for entry = 50017031

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176604(2-(3-((2-fluoro-4-(trifluoromethyl)benzyl)carbamoy...)

EC50: 500nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176606(2-(3-((3-fluoro-4-(trifluoromethyl)benzyl)carbamoy...)

EC50: 500nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50107546(2-(3-((4-(trifluoromethyl)benzyl)carbamoyl)-4-meth...)

EC50: 70nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176606(2-(3-((3-fluoro-4-(trifluoromethyl)benzyl)carbamoy...)

EC50: 1.60E+3nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Mus musculus)
University Of Tokyo

Curated by ChEMBL

BDBM50176605((S)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 1.00E+3nMAssay Description:Agonist activity at mouse PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176607(2-(3-((4-fluoro-3-(trifluoromethyl)benzamido)methy...)

EC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176608((2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]c...)

EC50: 1.90E+3nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL DrugBank MMDB PC cid PC sid PDB Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50131739((+/-)-2-(4-methoxy-3-((4-(trifluoromethyl)benzamid...)

EC50: 2.00E+3nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176605((S)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 630nMAssay Description:Agonist activity at human PPARalpha containing wild-type I272F domain transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176605((S)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 10nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176608((2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]c...)

EC50: 10nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL DrugBank MMDB PC cid PC sid PDB Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176607(2-(3-((4-fluoro-3-(trifluoromethyl)benzamido)methy...)

EC50: 250nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50131739((+/-)-2-(4-methoxy-3-((4-(trifluoromethyl)benzamid...)

EC50: 130nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176606(2-(3-((3-fluoro-4-(trifluoromethyl)benzyl)carbamoy...)

EC50: 25nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50131739((+/-)-2-(4-methoxy-3-((4-(trifluoromethyl)benzamid...)

EC50: 10nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176609((R)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 700nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176609((R)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176604(2-(3-((2-fluoro-4-(trifluoromethyl)benzyl)carbamoy...)

EC50: 1.00E+3nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50107546(2-(3-((4-(trifluoromethyl)benzyl)carbamoyl)-4-meth...)

EC50: 700nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176609((R)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 180nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176605((S)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 4.90E+3nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176604(2-(3-((2-fluoro-4-(trifluoromethyl)benzyl)carbamoy...)

EC50: 20nMAssay Description:Agonist activity at PPARalpha transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176607(2-(3-((4-fluoro-3-(trifluoromethyl)benzamido)methy...)

EC50: 2.00E+3nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50107546(2-(3-((4-(trifluoromethyl)benzyl)carbamoyl)-4-meth...)

EC50: 3.00E+3nMAssay Description:Agonist activity at PPARgamma transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176608((2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]c...)

EC50: 12nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL DrugBank MMDB PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL

BDBM50176605((S)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 40nMAssay Description:Agonist activity at PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Mus musculus)
University Of Tokyo

Curated by ChEMBL

BDBM50176605((S)-2-(3-((3-fluoro-4-(trifluoromethyl)benzamido)m...)

EC50: 130nMAssay Description:Agonist activity at mouse PPARdelta transfected in HEK293 cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed