Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50037666
TargetOxytocin receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177595((2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[...)
Affinity DataIC50:  12nMAssay Description:Antagonism of OT-induced response at OT receptor in rat uterine stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177599(CHEMBL202447 | [2-chloro-4-(3-methyl-pyrazol-1-yl)...)
Affinity DataIC50:  91.5nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177591(CHEMBL203513 | [2-chloro-4-(1-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  183nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177597(CHEMBL203739 | [2-bromo-4-(3-methyl-pyrazol-1-yl)-...)
Affinity DataIC50:  296nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177594(CHEMBL381763 | [2-chloro-4-(5-methyl-pyrazol-1-yl)...)
Affinity DataIC50:  390nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177598((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  413nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177600(CHEMBL205013 | [2-chloro-4-(3-methyl-pyrazol-1-yl)...)
Affinity DataIC50:  475nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  493nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataIC50:  778nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177601((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  933nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  1.26E+3nMAssay Description:Antagonism of OT-induced response at OT receptor in rat uterine stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177591(CHEMBL203513 | [2-chloro-4-(1-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  1.78E+3nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50:  5.95E+3nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V1a receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonism of AVP-induced response at V1a receptor in isolated rat tail arteriesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177593((5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)...)
Affinity DataEC50:  0.740nMAssay Description:Binding to human V2 receptor expressed in LV2 cells by cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50177592((5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6...)
Affinity DataEC50:  1.67nMAssay Description:Binding to human V2 receptor expressed in LV2 cells by cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed