Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50017112
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177615((R)-2-(5-(2,3-difluorobenzylthio)-2-aminothiazolo[...)
Affinity DataIC50:  9.5nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177611(2-(5-(2,3-difluorobenzylthio)-2-aminothiazolo[4,5-...)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177602(2-(5-(3-phenoxybenzylthio)-2-aminothiazolo[4,5-d]p...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177607((R)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimi...)
Affinity DataIC50:  120nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177604(5-(2,3-difluorobenzylthio)-2-aminothiazolo[4,5-d]p...)
Affinity DataIC50:  270nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177613((R)-2-(5-(3-phenoxybenzylthio)-2-aminothiazolo[4,5...)
Affinity DataIC50:  350nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177606(5-(3-phenoxybenzylthio)-2-aminothiazolo[4,5-d]pyri...)
Affinity DataIC50:  480nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177614(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimidin-7-o...)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177612((S)-2-(5-(3-phenoxybenzylthio)-2-aminothiazolo[4,5...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177605((S)-2-(2-amino-5-(benzylthio)thiazolo[4,5-d]pyrimi...)
Affinity DataIC50:  3.90E+3nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177603(2-(2-amino-5-(pentylthio)thiazolo[4,5-d]pyrimidin-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177610(5-(benzylthio)thiazolo[4,5-d]pyrimidine-2,7-diamin...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177608(2-amino-5-(pentylthio)thiazolo[4,5-d]pyrimidin-7-o...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50177609(5-(pentylthio)thiazolo[4,5-d]pyrimidin-7-ol | CHEM...)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [125I]IL8 from human recombinant CXCR2 expressed in HEK293 membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed