Compile Data Set for Download or QSAR
maximum 50k data
Found 62 Enz. Inhib. hit(s) with all data for entry = 50017787
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186457(1-(4-(5-(2-(4,6-dimethylpyridin-2-ylamino)thiazol-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186484(1-(4-(5-(2-(4,6-dimethylpyridin-2-ylamino)thiazol-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186487(CHEMBL209881 | N-(5-(4-methoxy-2-methyl-5-(morphol...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186478(1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...)
Affinity DataIC50:  7nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186459(CHEMBL211842 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  9nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186456(CHEMBL211355 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186461(CHEMBL209163 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  14nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186474(1-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186480(CHEMBL379114 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  18nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186479(CHEMBL208901 | N-(5-(5-(1-(2-(dimethylamino)acetyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186470(CHEMBL211291 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  20nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186496(CHEMBL210985 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  29nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186466(1-(4-(2-hydroxy-5-(2-(pyridin-2-ylamino)thiazol-5-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186472(CHEMBL209004 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186467(CHEMBL210528 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  34nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186488(1-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50:  34nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186477(CHEMBL380058 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  47nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186468(CHEMBL206905 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  60nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186486(1-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50:  83nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186495(CHEMBL210243 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50182833(CHEMBL382362 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  96nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186498(CHEMBL209400 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  210nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186497(CHEMBL211136 | N-(5-(4-acetamido-3-(1-acetylpipera...)
Affinity DataIC50:  250nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186476(CHEMBL210932 | N-(5-(5-(1-ethylpiperazine-4-carbon...)
Affinity DataIC50:  260nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186463(CHEMBL209009 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  290nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186469(2-((5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy...)
Affinity DataIC50:  320nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186464(2-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio...)
Affinity DataIC50:  370nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186492(CHEMBL373513 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  600nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186482(1-(4-(3-(2-(pyridin-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50:  690nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186458(CHEMBL273966 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  820nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186483(CHEMBL211021 | N-(5-((3-(1-acetylpiperazine-4-carb...)
Affinity DataIC50:  930nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186473(CHEMBL210735 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  940nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186471(CHEMBL437495 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  970nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50182839(CHEMBL205799 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Insulin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186489(CHEMBL210046 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186475(CHEMBL426685 | N-(5-(((3-(1-acetylpiperazine-4-car...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186494(CHEMBL209056 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of BtkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186491(1-(4-(3-(2-(pyrazin-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50:  6.06E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186455(1-(4-(3-(2-(thiazol-2-ylamino)thiazol-5-ylthio)ben...)
Affinity DataIC50:  7.07E+3nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of TxkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of TecMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186485(CHEMBL210599 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186465(CHEMBL377355 | N-(5-((3-(1-acetylpiperazine-4-carb...)
Affinity DataIC50:  2.23E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186460(CHEMBL209148 | N-(5-(5-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of PKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50186462(CHEMBL208867 | N-(5-(3-(1-acetylpiperazine-4-carbo...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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