Compile Data Set for Download or QSAR
maximum 50k data
Found 100 Enz. Inhib. hit(s) with all data for entry = 50017845
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  40nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187340((6-Chloro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  100nMAssay Description:Antiproliferative activity against mouse 32Dcl3 cell line expressing FLT3-ITDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  100nMAssay Description:Antiproliferative activity against mouse 32Dcl3 cell line expressing wildtype FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187369((5-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  170nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  171nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187340((6-Chloro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM6581((5-Hydroxy-1H-2-indolyl)(1H-2-indolyl)-methanone |...)
Affinity DataIC50:  200nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187357((4-Methyl-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM6574((6-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...)
Affinity DataIC50:  300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM6573((5-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...)
Affinity DataIC50:  300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  300nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187365((4-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  340nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187348((5-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50:  400nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  458nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing KIT V558D mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187356((5-Fluoro-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50:  500nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing wildtype KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187361((4-Chloro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  500nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing KIT V558D mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  500nMAssay Description:Inhibition of DNA synthesis in IL3 dependent FDC-P1 cells expressing wildtype KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187366((5-Methoxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  510nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187344((5-Hydroxy-1H-indol-2-yl)-(6-methoxy-1H-indol-2-yl...)
Affinity DataIC50:  530nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM6581((5-Hydroxy-1H-2-indolyl)(1H-2-indolyl)-methanone |...)
Affinity DataIC50:  570nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187367((5-Hydroxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  580nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187364((6-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  590nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187365((4-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  620nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187344((5-Hydroxy-1H-indol-2-yl)-(6-methoxy-1H-indol-2-yl...)
Affinity DataIC50:  650nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187373((5-Hydroxy-1H-indol-2-yl)-(4-methoxy-1H-indol-2-yl...)
Affinity DataIC50:  670nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187357((4-Methyl-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50:  700nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187369((5-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  730nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187362((5-Hydroxy-1H-indol-2-yl)-(5-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  740nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187349((5-fluoro-1H-indol-2-yl)-(1H-indol-2-yl)methanone ...)
Affinity DataIC50:  760nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187353((6-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50:  840nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187348((5-Fluoro-1H-indol-2-yl)-(5-methoxy-1H-indol-2-yl)...)
Affinity DataIC50:  880nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM6574((6-Methoxy-1H-2-indolyl)(1H-2-indolyl)methanone | ...)
Affinity DataIC50:  890nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187361((4-Chloro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  920nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187373((5-Hydroxy-1H-indol-2-yl)-(4-methoxy-1H-indol-2-yl...)
Affinity DataIC50:  960nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187345((5-Hydroxy-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  960nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187371((6-Methoxy-1H-indol-2-yl)-[5-(2-piperidin-1-yl-eth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187355(CHEMBL207483 | di(1H-indol-2-yl)methanone)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187364((6-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM33408(AG1295 | CHEMBL7724 | cid_2048)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187367((5-Hydroxy-1H-indol-2-yl)-(6-methyl-1H-indol-2-yl)...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of endogenous FLT3 in EOL1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187357((4-Methyl-1H-indol-2-yl)-[5-(2-piperidin-1-yl-etho...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human PDGFR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mus musculus (mouse))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187359((5-Fluoro-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of endogenous PDGFR in Swiss3T3 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50187351(Bis-(5-hydroxy-1H-indol-2-yl)-methanone | CHEMBL37...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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