Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50000589
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.570nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.660nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  1nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  1nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  2nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  2nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  3.10nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D1 using SCH-23390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  4.30nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  6.5nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  7.20nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  12nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  12nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  36nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  36nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB4101 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  94nMAssay Description:The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  94nMAssay Description:The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  550nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  550nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  800nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  800nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed