Compile Data Set for Download or QSAR
maximum 50k data
Found 60 Enz. Inhib. hit(s) with all data for entry = 50018166
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192214(3-(4-tert-butylphenyl)-4-cyano-5-(ethylthio)thioph...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191962(3-biphenyl-4-yl-4-cyano-1-methyl-5-methylsulfanyl-...)
Affinity DataEC50:  474nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192215(3-(4-tert-butylphenyl)-4-cyano-5-(propylthio)thiop...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192216(3-(4-tert-butylphenyl)-4-cyano-5-ethylthiophene-2-...)
Affinity DataEC50:  1.22E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192215(3-(4-tert-butylphenyl)-4-cyano-5-(propylthio)thiop...)
Affinity DataEC50:  2.89E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192217(3-(4-tert-butylphenyl)-4-cyano-5-(pyrrolidin-1-yl)...)
Affinity DataEC50:  1.14E+3nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50094024((+/-) Propane-2-sulfonic acid [2-(4'-cyano-bipheny...)
Affinity DataEC50:  420nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191962(3-biphenyl-4-yl-4-cyano-1-methyl-5-methylsulfanyl-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191962(3-biphenyl-4-yl-4-cyano-1-methyl-5-methylsulfanyl-...)
Affinity DataEC50:  174nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192218(3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfonyl)t...)
Affinity DataEC50:  1.81E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192219(3-(4-tert-butylphenyl)-4-cyano-1-methyl-5-(methylt...)
Affinity DataEC50:  1.42E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192214(3-(4-tert-butylphenyl)-4-cyano-5-(ethylthio)thioph...)
Affinity DataEC50:  440nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192220(CHEMBL384175 | ethyl 3-(4-tert-butylphenyl)-4-cyan...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192221(3-(4-tert-butylphenyl)-4-cyano-5-(trifluoromethyl)...)
Affinity DataEC50:  273nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191959(3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)thiop...)
Affinity DataEC50:  214nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192219(3-(4-tert-butylphenyl)-4-cyano-1-methyl-5-(methylt...)
Affinity DataEC50:  684nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192217(3-(4-tert-butylphenyl)-4-cyano-5-(pyrrolidin-1-yl)...)
Affinity DataEC50:  1.01E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192222(3-(4-tert-butylphenyl)-4-cyano-5-(dimethylamino)th...)
Affinity DataEC50:  474nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192216(3-(4-tert-butylphenyl)-4-cyano-5-ethylthiophene-2-...)
Affinity DataEC50:  216nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192217(3-(4-tert-butylphenyl)-4-cyano-5-(pyrrolidin-1-yl)...)
Affinity DataEC50:  2.43E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192223(3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfinyl)t...)
Affinity DataEC50:  489nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192218(3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfonyl)t...)
Affinity DataEC50:  333nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192223(3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfinyl)t...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191959(3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)thiop...)
Affinity DataEC50:  97nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192224(3-(4-tert-butylphenyl)-4-cyano-5-(phenylthio)thiop...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192225(3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)furan...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50094024((+/-) Propane-2-sulfonic acid [2-(4'-cyano-bipheny...)
Affinity DataEC50:  559nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50094019(CHEMBL334920 | N-(2-(4-(thiophen-3-yl)phenyl)propy...)
Affinity DataEC50:  660nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192226(3-(4-tert-butylphenyl)-4-cyanothiophene-2-carboxyl...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192222(3-(4-tert-butylphenyl)-4-cyano-5-(dimethylamino)th...)
Affinity DataEC50:  176nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192222(3-(4-tert-butylphenyl)-4-cyano-5-(dimethylamino)th...)
Affinity DataEC50:  2.85E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50094024((+/-) Propane-2-sulfonic acid [2-(4'-cyano-bipheny...)
Affinity DataEC50:  1.91E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192224(3-(4-tert-butylphenyl)-4-cyano-5-(phenylthio)thiop...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192226(3-(4-tert-butylphenyl)-4-cyanothiophene-2-carboxyl...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191962(3-biphenyl-4-yl-4-cyano-1-methyl-5-methylsulfanyl-...)
Affinity DataEC50:  394nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192220(CHEMBL384175 | ethyl 3-(4-tert-butylphenyl)-4-cyan...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50191959(3-(4-tert-butylphenyl)-4-cyano-5-(methylthio)thiop...)
Affinity DataEC50:  309nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192226(3-(4-tert-butylphenyl)-4-cyanothiophene-2-carboxyl...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192219(3-(4-tert-butylphenyl)-4-cyano-1-methyl-5-(methylt...)
Affinity DataEC50:  663nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192216(3-(4-tert-butylphenyl)-4-cyano-5-ethylthiophene-2-...)
Affinity DataEC50:  183nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192227(3-biphenyl-4-yl-4-cyano-5-methylsulfanyl-thiophene...)
Affinity DataEC50:  795nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192228(3-(4-tert-butylphenyl)-4-cyano-5-(isopropylthio)th...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192221(3-(4-tert-butylphenyl)-4-cyano-5-(trifluoromethyl)...)
Affinity DataEC50:  488nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192219(3-(4-tert-butylphenyl)-4-cyano-1-methyl-5-(methylt...)
Affinity DataEC50:  554nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192221(3-(4-tert-butylphenyl)-4-cyano-5-(trifluoromethyl)...)
Affinity DataEC50:  78nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192218(3-(4-tert-butylphenyl)-4-cyano-5-(methylsulfonyl)t...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192227(3-biphenyl-4-yl-4-cyano-5-methylsulfanyl-thiophene...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192220(CHEMBL384175 | ethyl 3-(4-tert-butylphenyl)-4-cyan...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192222(3-(4-tert-butylphenyl)-4-cyano-5-(dimethylamino)th...)
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50192229(3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...)
Affinity DataEC50:  3.80E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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