Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50018553
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM16016(CHEMBL437747 | N-cyclohexyl-4-[4-(3,4-dichlorophen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM16016(CHEMBL437747 | N-cyclohexyl-4-[4-(3,4-dichlorophen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15913(2-pyridinecarboxamide deriv. 8c | 4-Amino-5-cyano-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194856(CHEMBL374269 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  23nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15918(2-pyridinecarboxamide deriv. 12 | 4-Amino-5-chloro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196993(4-amino-N-((4-chloropyridin-3-yl)methyl)-5-cyano-6...)
Affinity DataIC50:  30nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196992((Z)-4-(3-(4-(3-(dimethylamino)propoxy)phenyl)-3-hy...)
Affinity DataIC50:  34nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196997(CHEMBL240859 | N-(4-(phenylsulfinyl)benzyl)-4-amin...)
Affinity DataIC50:  50nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196994(4-amino-5-cyano-6-ethoxy-N-(2-(5-nitropyridin-2-yl...)
Affinity DataIC50:  61nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15918(2-pyridinecarboxamide deriv. 12 | 4-Amino-5-chloro...)
Affinity DataIC50:  74nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194908(CHEMBL219112 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  81nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194904(CHEMBL375795 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  96nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15913(2-pyridinecarboxamide deriv. 8c | 4-Amino-5-cyano-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196998(CHEMBL391502 | N-(4-(phenylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  130nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196995(CHEMBL239785 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196996(CHEMBL391579 | N-(4-(methylsulfonyl)benzyl)-5-cyan...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15913(2-pyridinecarboxamide deriv. 8c | 4-Amino-5-cyano-...)
Affinity DataEC50:  318nMAssay Description:Inhibition of c-Jun phosphorylation in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed