Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50020004
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209580(CHEMBL415659 | [Ncy(isopropyl)7]acyline)
Affinity DataIC50:  0.310nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50102456(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)]-D-[Aph(A...)
Affinity DataIC50:  0.520nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209587(CHEMBL387499 | [D-Ncy(methyl)10] acyline)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209594(CHEMBL227861 | [D-Ncy(2-naphthyl)1]acyline)
Affinity DataIC50:  0.730nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209583(CHEMBL427438 | [Ncy(methyl)10]acyline)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209590(CHEMBL227451 | [D-Ncy(isopropyl)7]acyline)
Affinity DataIC50:  0.810nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209599(CHEMBL434371 | [D-Ncy(SO,methyl)10]acyline)
Affinity DataIC50:  0.830nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209598(CHEMBL389248 | [Ncy(SO,methyl)10]acyline)
Affinity DataIC50:  0.870nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209595(CHEMBL441211 | [Ncy(SO,isopropyl)7]acyline)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209582(CHEMBL388369 | [Ncy(methyl)4]acyline)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209591(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Atz)]-D-[Aph(...)
Affinity DataIC50:  1.36nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209591(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Atz)]-D-[Aph(...)
Affinity DataIC50:  1.40nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50102456(Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Aph(Ac)]-D-[Aph(A...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209583(CHEMBL427438 | [Ncy(methyl)10]acyline)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209587(CHEMBL387499 | [D-Ncy(methyl)10] acyline)
Affinity DataIC50:  1.70nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209585(CHEMBL414344 | [Ncy(2-naphthyl)1]acyline)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209582(CHEMBL388369 | [Ncy(methyl)4]acyline)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209580(CHEMBL415659 | [Ncy(isopropyl)7]acyline)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209588(CHEMBL427269 | [D-Ncy(SO,isopropyl)7]acyline)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209595(CHEMBL441211 | [Ncy(SO,isopropyl)7]acyline)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209594(CHEMBL227861 | [D-Ncy(2-naphthyl)1]acyline)
Affinity DataIC50:  4.40nMAssay Description:Antagonist activity at rat GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209586(CHEMBL415432 | [Ncy(SO,methyl)4]acyline)
Affinity DataIC50:  4.60nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209593(CHEMBL228197 | [D-Gln3,Ncy(isopropyl)7]acyline)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209581(CHEMBL389945 | [D-Ncy(SO,methyl)4]acyline)
Affinity DataIC50:  6.90nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209596(CHEMBL425486 | [D-Gln3,Ncy(SO,isopropyl)7]acyline)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209597(CHEMBL268297 | [D-Ncy(methyl)4]acyline)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209589(CHEMBL428795 | [D-Gln3,D-Ncy(isopropyl)7]acyline)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209584(CHEMBL415380 | [D-Gln3,D-Ncy(SO,isopropyl)7]acylin...)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209592(CHEMBL373725 | [D-Gln3,D-Ncy(SO2,isopropyl)7]acyli...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50209600(CHEMBL373724 | [D-Gln3,Ncy(SO2,isopropyl)7]acyline)
Affinity DataIC50:  3.82E+3nMAssay Description:Antagonist activity at human GnRHR expressed in HEK293 cells assessed as inhibition of GnRH-induced luciferase response by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed