BindingDB logo
myBDB logout

PubMed code 18556198

Compile data set for download or QSAR
Found 125 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243187
PNG
((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...)
Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 43n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243129
PNG
((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 70n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243185
PNG
((S)-2-amino-6-(benzylamino)-1-(isoindolin-2-yl)hex...)
Show SMILES N[C@@H](CCCCNCc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C21H27N3O/c22-20(12-6-7-13-23-14-17-8-2-1-3-9-17)21(25)24-15-18-10-4-5-11-19(18)16-24/h1-5,8-11,20,23H,6-7,12-16,22H2/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 111n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243185
PNG
((S)-2-amino-6-(benzylamino)-1-(isoindolin-2-yl)hex...)
Show SMILES N[C@@H](CCCCNCc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C21H27N3O/c22-20(12-6-7-13-23-14-17-8-2-1-3-9-17)21(25)24-15-18-10-4-5-11-19(18)16-24/h1-5,8-11,20,23H,6-7,12-16,22H2/t20-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 117n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50225437
PNG
((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243129
PNG
((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243187
PNG
((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...)
Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 169n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243133
PNG
((S)-benzyl 5-amino-6-(isoindolin-2-yl)-6-oxohexylc...)
Show SMILES N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H27N3O3/c23-20(21(26)25-14-18-10-4-5-11-19(18)15-25)12-6-7-13-24-22(27)28-16-17-8-2-1-3-9-17/h1-5,8-11,20H,6-7,12-16,23H2,(H,24,27)/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243185
PNG
((S)-2-amino-6-(benzylamino)-1-(isoindolin-2-yl)hex...)
Show SMILES N[C@@H](CCCCNCc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C21H27N3O/c22-20(12-6-7-13-23-14-17-8-2-1-3-9-17)21(25)24-15-18-10-4-5-11-19(18)16-24/h1-5,8-11,20,23H,6-7,12-16,22H2/t20-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243132
PNG
((S)-2,6-diamino-1-(isoindolin-2-yl)hexan-1-one | C...)
Show SMILES NCCCC[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H21N3O/c15-8-4-3-7-13(16)14(18)17-9-11-5-1-2-6-12(11)10-17/h1-2,5-6,13H,3-4,7-10,15-16H2/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243319
PNG
(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 290n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50225437
PNG
((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 290n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243187
PNG
((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...)
Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 316n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243186
PNG
((S)-2-amino-6-(dibenzylamino)-1-(isoindolin-2-yl)h...)
Show SMILES N[C@@H](CCCCN(Cc1ccccc1)Cc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C28H33N3O/c29-27(28(32)31-21-25-15-7-8-16-26(25)22-31)17-9-10-18-30(19-23-11-3-1-4-12-23)20-24-13-5-2-6-14-24/h1-8,11-16,27H,9-10,17-22,29H2/t27-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 365n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243319
PNG
(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 380n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243188
PNG
((S)-2-amino-6-(dinaphthalen-2-ylamino)-1-(isoindol...)
Show SMILES N[C@@H](CCCCN(c1ccc2ccccc2c1)c1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C34H33N3O/c35-33(34(38)36-23-29-13-5-6-14-30(29)24-36)15-7-8-20-37(31-18-16-25-9-1-3-11-27(25)21-31)32-19-17-26-10-2-4-12-28(26)22-32/h1-6,9-14,16-19,21-22,33H,7-8,15,20,23-24,35H2/t33-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 416n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243188
PNG
((S)-2-amino-6-(dinaphthalen-2-ylamino)-1-(isoindol...)
Show SMILES N[C@@H](CCCCN(c1ccc2ccccc2c1)c1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C34H33N3O/c35-33(34(38)36-23-29-13-5-6-14-30(29)24-36)15-7-8-20-37(31-18-16-25-9-1-3-11-27(25)21-31)32-19-17-26-10-2-4-12-28(26)22-32/h1-6,9-14,16-19,21-22,33H,7-8,15,20,23-24,35H2/t33-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 479n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243132
PNG
((S)-2,6-diamino-1-(isoindolin-2-yl)hexan-1-one | C...)
Show SMILES NCCCC[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H21N3O/c15-8-4-3-7-13(16)14(18)17-9-11-5-1-2-6-12(11)10-17/h1-2,5-6,13H,3-4,7-10,15-16H2/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 500n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50242854
PNG
((2S,3S)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 540n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243186
PNG
((S)-2-amino-6-(dibenzylamino)-1-(isoindolin-2-yl)h...)
Show SMILES N[C@@H](CCCCN(Cc1ccccc1)Cc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C28H33N3O/c29-27(28(32)31-21-25-15-7-8-16-26(25)22-31)17-9-10-18-30(19-23-11-3-1-4-12-23)20-24-13-5-2-6-14-24/h1-8,11-16,27H,9-10,17-22,29H2/t27-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 666n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243243
PNG
(CHEMBL527647 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1cccc2ccccc12)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-17-7-1-2-8-18(17)15-26)22-12-19(13-24-22)25-21-11-5-9-16-6-3-4-10-20(16)21/h1-11,19,22,24-25H,12-15H2/t19-,22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 710n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243128
PNG
((2S,3R)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 800n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243243
PNG
(CHEMBL527647 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1cccc2ccccc12)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-17-7-1-2-8-18(17)15-26)22-12-19(13-24-22)25-21-11-5-9-16-6-3-4-10-20(16)21/h1-11,19,22,24-25H,12-15H2/t19-,22-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 860n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243245
PNG
(CHEMBL488493 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 910n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243130
PNG
((2S,3R)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50242854
PNG
((2S,3S)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243128
PNG
((2S,3R)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243245
PNG
(CHEMBL488493 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50242851
PNG
((2S,3S)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243244
PNG
(((2S,4S)-4-(dinaphthalen-1-ylamino)pyrrolidin-2-yl...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)N(c1cccc2ccccc12)c1cccc2ccccc12)N1Cc2ccccc2C1
Show InChI InChI=1S/C33H29N3O/c37-33(35-21-25-11-1-2-12-26(25)22-35)30-19-27(20-34-30)36(31-17-7-13-23-9-3-5-15-28(23)31)32-18-8-14-24-10-4-6-16-29(24)32/h1-18,27,30,34H,19-22H2/t27-,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243132
PNG
((S)-2,6-diamino-1-(isoindolin-2-yl)hexan-1-one | C...)
Show SMILES NCCCC[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H21N3O/c15-8-4-3-7-13(16)14(18)17-9-11-5-1-2-6-12(11)10-17/h1-2,5-6,13H,3-4,7-10,15-16H2/t13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.78E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243186
PNG
((S)-2-amino-6-(dibenzylamino)-1-(isoindolin-2-yl)h...)
Show SMILES N[C@@H](CCCCN(Cc1ccccc1)Cc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C28H33N3O/c29-27(28(32)31-21-25-15-7-8-16-26(25)22-31)17-9-10-18-30(19-23-11-3-1-4-12-23)20-24-13-5-2-6-14-24/h1-8,11-16,27H,9-10,17-22,29H2/t27-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.39E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243133
PNG
((S)-benzyl 5-amino-6-(isoindolin-2-yl)-6-oxohexylc...)
Show SMILES N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H27N3O3/c23-20(21(26)25-14-18-10-4-5-11-19(18)15-25)12-6-7-13-24-22(27)28-16-17-8-2-1-3-9-17/h1-5,8-11,20H,6-7,12-16,23H2,(H,24,27)/t20-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243080
PNG
((2S,3S)-2-amino-1-(5-iodoisoindolin-2-yl)-3-methyl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(I)cc2C1
Show InChI InChI=1S/C14H19IN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243319
PNG
(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.65E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243130
PNG
((2S,3R)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243242
PNG
(((2S,4S)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243242
PNG
(((2S,4S)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243317
PNG
(((2S,4R)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243188
PNG
((S)-2-amino-6-(dinaphthalen-2-ylamino)-1-(isoindol...)
Show SMILES N[C@@H](CCCCN(c1ccc2ccccc2c1)c1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C34H33N3O/c35-33(34(38)36-23-29-13-5-6-14-30(29)24-36)15-7-8-20-37(31-18-16-25-9-1-3-11-27(25)21-31)32-19-17-26-10-2-4-12-28(26)22-32/h1-6,9-14,16-19,21-22,33H,7-8,15,20,23-24,35H2/t33-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.67E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243079
PNG
((2S,3S)-2-amino-1-(5-bromoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(Br)cc2C1
Show InChI InChI=1S/C14H19BrN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50242851
PNG
((2S,3S)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243318
PNG
(((2S,4R)-4-(dibenzylamino)pyrrolidin-2-yl)(isoindo...)
Show SMILES O=C([C@@H]1C[C@H](CN1)N(Cc1ccccc1)Cc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C27H29N3O/c31-27(30-19-23-13-7-8-14-24(23)20-30)26-15-25(16-28-26)29(17-21-9-3-1-4-10-21)18-22-11-5-2-6-12-22/h1-14,25-26,28H,15-20H2/t25-,26+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50242931
PNG
((2S,3S)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243079
PNG
((2S,3S)-2-amino-1-(5-bromoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(Br)cc2C1
Show InChI InChI=1S/C14H19BrN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.90E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243243
PNG
(CHEMBL527647 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1cccc2ccccc12)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-17-7-1-2-8-18(17)15-26)22-12-19(13-24-22)25-21-11-5-9-16-6-3-4-10-20(16)21/h1-11,19,22,24-25H,12-15H2/t19-,22-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.97E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243245
PNG
(CHEMBL488493 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.77E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243317
PNG
(((2S,4R)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.90E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243315
PNG
(((2S,4S)-4-(dinaphthalen-2-ylamino)pyrrolidin-2-yl...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)N(c1ccc2ccccc2c1)c1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C33H29N3O/c37-33(35-21-27-11-5-6-12-28(27)22-35)32-19-31(20-34-32)36(29-15-13-23-7-1-3-9-25(23)17-29)30-16-14-24-8-2-4-10-26(24)18-30/h1-18,31-32,34H,19-22H2/t31-,32-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.69E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243128
PNG
((2S,3R)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.10E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50242852
PNG
((2S,3S)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.30E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243079
PNG
((2S,3S)-2-amino-1-(5-bromoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(Br)cc2C1
Show InChI InChI=1S/C14H19BrN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.40E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50242931
PNG
((2S,3S)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.60E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50242852
PNG
((2S,3S)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243315
PNG
(((2S,4S)-4-(dinaphthalen-2-ylamino)pyrrolidin-2-yl...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)N(c1ccc2ccccc2c1)c1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C33H29N3O/c37-33(35-21-27-11-5-6-12-28(27)22-35)32-19-31(20-34-32)36(29-15-13-23-7-1-3-9-25(23)17-29)30-16-14-24-8-2-4-10-26(24)18-30/h1-18,31-32,34H,19-22H2/t31-,32-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.02E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243244
PNG
(((2S,4S)-4-(dinaphthalen-1-ylamino)pyrrolidin-2-yl...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)N(c1cccc2ccccc12)c1cccc2ccccc12)N1Cc2ccccc2C1
Show InChI InChI=1S/C33H29N3O/c37-33(35-21-25-11-1-2-12-26(25)22-35)30-19-27(20-34-30)36(31-17-7-13-23-9-3-5-15-28(23)31)32-18-8-14-24-10-4-6-16-29(24)32/h1-18,27,30,34H,19-22H2/t27-,30-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50242852
PNG
((2S,3S)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.22E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243131
PNG
((2S,3R)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243078
PNG
((2S,3S)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243318
PNG
(((2S,4R)-4-(dibenzylamino)pyrrolidin-2-yl)(isoindo...)
Show SMILES O=C([C@@H]1C[C@H](CN1)N(Cc1ccccc1)Cc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C27H29N3O/c31-27(30-19-23-13-7-8-14-24(23)20-30)26-15-25(16-28-26)29(17-21-9-3-1-4-10-21)18-22-11-5-2-6-12-22/h1-14,25-26,28H,15-20H2/t25-,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243242
PNG
(((2S,4S)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.31E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243244
PNG
(((2S,4S)-4-(dinaphthalen-1-ylamino)pyrrolidin-2-yl...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)N(c1cccc2ccccc12)c1cccc2ccccc12)N1Cc2ccccc2C1
Show InChI InChI=1S/C33H29N3O/c37-33(35-21-25-11-1-2-12-26(25)22-35)30-19-27(20-34-30)36(31-17-7-13-23-9-3-5-15-28(23)31)32-18-8-14-24-10-4-6-16-29(24)32/h1-18,27,30,34H,19-22H2/t27-,30-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.61E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243129
PNG
((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.15E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50242854
PNG
((2S,3S)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243316
PNG
(((2S,4R)-4-aminopyrrolidin-2-yl)(isoindolin-2-yl)m...)
Show SMILES N[C@H]1CN[C@@H](C1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C13H17N3O/c14-11-5-12(15-6-11)13(17)16-7-9-3-1-2-4-10(9)8-16/h1-4,11-12,15H,5-8,14H2/t11-,12+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243318
PNG
(((2S,4R)-4-(dibenzylamino)pyrrolidin-2-yl)(isoindo...)
Show SMILES O=C([C@@H]1C[C@H](CN1)N(Cc1ccccc1)Cc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C27H29N3O/c31-27(30-19-23-13-7-8-14-24(23)20-30)26-15-25(16-28-26)29(17-21-9-3-1-4-10-21)18-22-11-5-2-6-12-22/h1-14,25-26,28H,15-20H2/t25-,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243081
PNG
((2S,3S)-2-amino-3-methyl-1-(5-nitroisoindolin-2-yl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)[N+]([O-])=O
Show InChI InChI=1S/C14H19N3O3/c1-3-9(2)13(15)14(18)16-7-10-4-5-12(17(19)20)6-11(10)8-16/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243080
PNG
((2S,3S)-2-amino-1-(5-iodoisoindolin-2-yl)-3-methyl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(I)cc2C1
Show InChI InChI=1S/C14H19IN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50225437
PNG
((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243317
PNG
(((2S,4R)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.98E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243188
PNG
((S)-2-amino-6-(dinaphthalen-2-ylamino)-1-(isoindol...)
Show SMILES N[C@@H](CCCCN(c1ccc2ccccc2c1)c1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C34H33N3O/c35-33(34(38)36-23-29-13-5-6-14-30(29)24-36)15-7-8-20-37(31-18-16-25-9-1-3-11-27(25)21-31)32-19-17-26-10-2-4-12-28(26)22-32/h1-6,9-14,16-19,21-22,33H,7-8,15,20,23-24,35H2/t33-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.13E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243243
PNG
(CHEMBL527647 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1cccc2ccccc12)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-17-7-1-2-8-18(17)15-26)22-12-19(13-24-22)25-21-11-5-9-16-6-3-4-10-20(16)21/h1-11,19,22,24-25H,12-15H2/t19-,22-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.10E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243316
PNG
(((2S,4R)-4-aminopyrrolidin-2-yl)(isoindolin-2-yl)m...)
Show SMILES N[C@H]1CN[C@@H](C1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C13H17N3O/c14-11-5-12(15-6-11)13(17)16-7-9-3-1-2-4-10(9)8-16/h1-4,11-12,15H,5-8,14H2/t11-,12+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.10E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50242851
PNG
((2S,3S)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.30E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243130
PNG
((2S,3R)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.70E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243080
PNG
((2S,3S)-2-amino-1-(5-iodoisoindolin-2-yl)-3-methyl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(I)cc2C1
Show InChI InChI=1S/C14H19IN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243185
PNG
((S)-2-amino-6-(benzylamino)-1-(isoindolin-2-yl)hex...)
Show SMILES N[C@@H](CCCCNCc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C21H27N3O/c22-20(12-6-7-13-23-14-17-8-2-1-3-9-17)21(25)24-15-18-10-4-5-11-19(18)16-24/h1-5,8-11,20,23H,6-7,12-16,22H2/t20-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243081
PNG
((2S,3S)-2-amino-3-methyl-1-(5-nitroisoindolin-2-yl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)[N+]([O-])=O
Show InChI InChI=1S/C14H19N3O3/c1-3-9(2)13(15)14(18)16-7-10-4-5-12(17(19)20)6-11(10)8-16/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243082
PNG
((2S,3S)-2-amino-1-(5-azidoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)N=[N+]=[N-]
Show InChI InChI=1S/C14H19N5O/c1-3-9(2)13(15)14(20)19-7-10-4-5-12(17-18-16)6-11(10)8-19/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243081
PNG
((2S,3S)-2-amino-3-methyl-1-(5-nitroisoindolin-2-yl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)[N+]([O-])=O
Show InChI InChI=1S/C14H19N3O3/c1-3-9(2)13(15)14(18)16-7-10-4-5-12(17(19)20)6-11(10)8-16/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243083
PNG
((2S,3S)-2-amino-3-methyl-1-(5H-pyrrolo[3,4-b]pyrid...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccnc2C1
Show InChI InChI=1S/C13H19N3O/c1-3-9(2)12(14)13(17)16-7-10-5-4-6-15-11(10)8-16/h4-6,9,12H,3,7-8,14H2,1-2H3/t9-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.69E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243186
PNG
((S)-2-amino-6-(dibenzylamino)-1-(isoindolin-2-yl)h...)
Show SMILES N[C@@H](CCCCN(Cc1ccccc1)Cc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C28H33N3O/c29-27(28(32)31-21-25-15-7-8-16-26(25)22-31)17-9-10-18-30(19-23-11-3-1-4-12-23)20-24-13-5-2-6-14-24/h1-8,11-16,27H,9-10,17-22,29H2/t27-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>6.25E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243081
PNG
((2S,3S)-2-amino-3-methyl-1-(5-nitroisoindolin-2-yl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)[N+]([O-])=O
Show InChI InChI=1S/C14H19N3O3/c1-3-9(2)13(15)14(18)16-7-10-4-5-12(17(19)20)6-11(10)8-16/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.60E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243316
PNG
(((2S,4R)-4-aminopyrrolidin-2-yl)(isoindolin-2-yl)m...)
Show SMILES N[C@H]1CN[C@@H](C1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C13H17N3O/c14-11-5-12(15-6-11)13(17)16-7-9-3-1-2-4-10(9)8-16/h1-4,11-12,15H,5-8,14H2/t11-,12+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.78E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50242854
PNG
((2S,3S)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.01E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243083
PNG
((2S,3S)-2-amino-3-methyl-1-(5H-pyrrolo[3,4-b]pyrid...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccnc2C1
Show InChI InChI=1S/C13H19N3O/c1-3-9(2)12(14)13(17)16-7-10-5-4-6-15-11(10)8-16/h4-6,9,12H,3,7-8,14H2,1-2H3/t9-,12-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.28E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50225437
PNG
((2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.00E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243082
PNG
((2S,3S)-2-amino-1-(5-azidoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)N=[N+]=[N-]
Show InChI InChI=1S/C14H19N5O/c1-3-9(2)13(15)14(20)19-7-10-4-5-12(17-18-16)6-11(10)8-19/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.60E+4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243080
PNG
((2S,3S)-2-amino-1-(5-iodoisoindolin-2-yl)-3-methyl...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(I)cc2C1
Show InChI InChI=1S/C14H19IN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243077
PNG
((2S,3S)-2-amino-1-(5-tert-butylisoindolin-2-yl)-3-...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(C)(C)C
Show InChI InChI=1S/C18H28N2O/c1-6-12(2)16(19)17(21)20-10-13-7-8-15(18(3,4)5)9-14(13)11-20/h7-9,12,16H,6,10-11,19H2,1-5H3/t12-,16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243131
PNG
((2S,3R)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50242853
PNG
((2S,3S)-2-amino-3-methyl-1-(4-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(C)c2C1
Show InChI InChI=1S/C15H22N2O/c1-4-10(2)14(16)15(18)17-8-12-7-5-6-11(3)13(12)9-17/h5-7,10,14H,4,8-9,16H2,1-3H3/t10-,14-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243245
PNG
(CHEMBL488493 | isoindolin-2-yl((2S,4S)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243077
PNG
((2S,3S)-2-amino-1-(5-tert-butylisoindolin-2-yl)-3-...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(C)(C)C
Show InChI InChI=1S/C18H28N2O/c1-6-12(2)16(19)17(21)20-10-13-7-8-15(18(3,4)5)9-14(13)11-20/h7-9,12,16H,6,10-11,19H2,1-5H3/t12-,16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243083
PNG
((2S,3S)-2-amino-3-methyl-1-(5H-pyrrolo[3,4-b]pyrid...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccnc2C1
Show InChI InChI=1S/C13H19N3O/c1-3-9(2)12(14)13(17)16-7-10-5-4-6-15-11(10)8-16/h4-6,9,12H,3,7-8,14H2,1-2H3/t9-,12-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243131
PNG
((2S,3R)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243078
PNG
((2S,3S)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243083
PNG
((2S,3S)-2-amino-3-methyl-1-(5H-pyrrolo[3,4-b]pyrid...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccnc2C1
Show InChI InChI=1S/C13H19N3O/c1-3-9(2)12(14)13(17)16-7-10-5-4-6-15-11(10)8-16/h4-6,9,12H,3,7-8,14H2,1-2H3/t9-,12-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243077
PNG
((2S,3S)-2-amino-1-(5-tert-butylisoindolin-2-yl)-3-...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(C)(C)C
Show InChI InChI=1S/C18H28N2O/c1-6-12(2)16(19)17(21)20-10-13-7-8-15(18(3,4)5)9-14(13)11-20/h7-9,12,16H,6,10-11,19H2,1-5H3/t12-,16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50242853
PNG
((2S,3S)-2-amino-3-methyl-1-(4-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(C)c2C1
Show InChI InChI=1S/C15H22N2O/c1-4-10(2)14(16)15(18)17-8-12-7-5-6-11(3)13(12)9-17/h5-7,10,14H,4,8-9,16H2,1-3H3/t10-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243130
PNG
((2S,3R)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243078
PNG
((2S,3S)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50242853
PNG
((2S,3S)-2-amino-3-methyl-1-(4-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(C)c2C1
Show InChI InChI=1S/C15H22N2O/c1-4-10(2)14(16)15(18)17-8-12-7-5-6-11(3)13(12)9-17/h5-7,10,14H,4,8-9,16H2,1-3H3/t10-,14-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50242852
PNG
((2S,3S)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50243315
PNG
(((2S,4S)-4-(dinaphthalen-2-ylamino)pyrrolidin-2-yl...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)N(c1ccc2ccccc2c1)c1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C33H29N3O/c37-33(35-21-27-11-5-6-12-28(27)22-35)32-19-31(20-34-32)36(29-15-13-23-7-1-3-9-25(23)17-29)30-16-14-24-8-2-4-10-26(24)18-30/h1-18,31-32,34H,19-22H2/t31-,32-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243078
PNG
((2S,3S)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243077
PNG
((2S,3S)-2-amino-1-(5-tert-butylisoindolin-2-yl)-3-...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(C)(C)C
Show InChI InChI=1S/C18H28N2O/c1-6-12(2)16(19)17(21)20-10-13-7-8-15(18(3,4)5)9-14(13)11-20/h7-9,12,16H,6,10-11,19H2,1-5H3/t12-,16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243129
PNG
((2S,3R)-2-amino-1-(5-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243079
PNG
((2S,3S)-2-amino-1-(5-bromoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(Br)cc2C1
Show InChI InChI=1S/C14H19BrN2O/c1-3-9(2)13(16)14(18)17-7-10-4-5-12(15)6-11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50243082
PNG
((2S,3S)-2-amino-1-(5-azidoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)N=[N+]=[N-]
Show InChI InChI=1S/C14H19N5O/c1-3-9(2)13(15)14(20)19-7-10-4-5-12(17-18-16)6-11(10)8-19/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP8 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50243131
PNG
((2S,3R)-2-amino-3-methyl-1-(5-(trifluoromethyl)iso...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1S/C15H19F3N2O/c1-3-9(2)13(19)14(21)20-7-10-4-5-12(15(16,17)18)6-11(10)8-20/h4-6,9,13H,3,7-8,19H2,1-2H3/t9-,13+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50242931
PNG
((2S,3S)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243128
PNG
((2S,3R)-2-amino-1-(4-fluoroisoindolin-2-yl)-3-meth...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C14H19FN2O/c1-3-9(2)13(16)14(18)17-7-10-5-4-6-12(15)11(10)8-17/h4-6,9,13H,3,7-8,16H2,1-2H3/t9-,13+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243082
PNG
((2S,3S)-2-amino-1-(5-azidoisoindolin-2-yl)-3-methy...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(cc2C1)N=[N+]=[N-]
Show InChI InChI=1S/C14H19N5O/c1-3-9(2)13(15)14(20)19-7-10-4-5-12(17-18-16)6-11(10)8-19/h4-6,9,13H,3,7-8,15H2,1-2H3/t9-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50242931
PNG
((2S,3S)-2-amino-3-methyl-1-(5-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccc(C)cc2C1
Show InChI InChI=1S/C15H22N2O/c1-4-11(3)14(16)15(18)17-8-12-6-5-10(2)7-13(12)9-17/h5-7,11,14H,4,8-9,16H2,1-3H3/t11-,14-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50242853
PNG
((2S,3S)-2-amino-3-methyl-1-(4-methylisoindolin-2-y...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2cccc(C)c2C1
Show InChI InChI=1S/C15H22N2O/c1-4-10(2)14(16)15(18)17-8-12-7-5-6-11(3)13(12)9-17/h5-7,10,14H,4,8-9,16H2,1-3H3/t10-,14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP9 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50242851
PNG
((2S,3S)-2-amino-1-(isoindolin-2-yl)-3-methylpentan...)
Show SMILES CC[C@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H20N2O/c1-3-10(2)13(15)14(17)16-8-11-6-4-5-7-12(11)9-16/h4-7,10,13H,3,8-9,15H2,1-2H3/t10-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.15E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243132
PNG
((S)-2,6-diamino-1-(isoindolin-2-yl)hexan-1-one | C...)
Show SMILES NCCCC[C@H](N)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C14H21N3O/c15-8-4-3-7-13(16)14(18)17-9-11-5-1-2-6-12(11)10-17/h1-2,5-6,13H,3-4,7-10,15-16H2/t13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.61E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243187
PNG
((S)-2-amino-1-(isoindolin-2-yl)-6-(naphthalen-2-yl...)
Show SMILES N[C@@H](CCCCNc1ccc2ccccc2c1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C24H27N3O/c25-23(24(28)27-16-20-9-3-4-10-21(20)17-27)11-5-6-14-26-22-13-12-18-7-1-2-8-19(18)15-22/h1-4,7-10,12-13,15,23,26H,5-6,11,14,16-17,25H2/t23-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.78E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243133
PNG
((S)-benzyl 5-amino-6-(isoindolin-2-yl)-6-oxohexylc...)
Show SMILES N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H27N3O3/c23-20(21(26)25-14-18-10-4-5-11-19(18)15-25)12-6-7-13-24-22(27)28-16-17-8-2-1-3-9-17/h1-5,8-11,20H,6-7,12-16,23H2,(H,24,27)/t20-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.45E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243242
PNG
(((2S,4S)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243319
PNG
(CHEMBL453582 | isoindolin-2-yl((2S,4R)-4-(naphthal...)
Show SMILES O=C([C@@H]1C[C@H](CN1)Nc1ccc2ccccc2c1)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H23N3O/c27-23(26-14-18-7-3-4-8-19(18)15-26)22-12-21(13-24-22)25-20-10-9-16-5-1-2-6-17(16)11-20/h1-11,21-22,24-25H,12-15H2/t21-,22+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.50E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243318
PNG
(((2S,4R)-4-(dibenzylamino)pyrrolidin-2-yl)(isoindo...)
Show SMILES O=C([C@@H]1C[C@H](CN1)N(Cc1ccccc1)Cc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C27H29N3O/c31-27(30-19-23-13-7-8-14-24(23)20-30)26-15-25(16-28-26)29(17-21-9-3-1-4-10-21)18-22-11-5-2-6-12-22/h1-14,25-26,28H,15-20H2/t25-,26+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243316
PNG
(((2S,4R)-4-aminopyrrolidin-2-yl)(isoindolin-2-yl)m...)
Show SMILES N[C@H]1CN[C@@H](C1)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C13H17N3O/c14-11-5-12(15-6-11)13(17)16-7-9-3-1-2-4-10(9)8-16/h1-4,11-12,15H,5-8,14H2/t11-,12+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50243317
PNG
(((2S,4R)-4-(benzylamino)pyrrolidin-2-yl)(isoindoli...)
Show SMILES O=C([C@@H]1C[C@H](CN1)NCc1ccccc1)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23N3O/c24-20(23-13-16-8-4-5-9-17(16)14-23)19-10-18(12-22-19)21-11-15-6-2-1-3-7-15/h1-9,18-19,21-22H,10-14H2/t18-,19+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP4 (unknown origin)


Bioorg Med Chem Lett 18: 4159-62 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.079
BindingDB Entry DOI: 10.7270/Q2KS6RC4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%