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Found 85 Enz. Inhib. hit(s) with all data for entry = 50026873
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM23120(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245066(CHEMBL527204 | N-(benzo[c][1,2,5]thiadiazol-4-yl)-...)
Affinity DataIC50:  1.35nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245066(CHEMBL527204 | N-(benzo[c][1,2,5]thiadiazol-4-yl)-...)
Affinity DataIC50:  2.02nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244890(CHEMBL472535 | N-(2-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245030(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrimidin-4-...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244993(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyridin-3-yl...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244993(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyridin-3-yl...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245030(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrimidin-4-...)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245065(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrazin-2-yl...)
Affinity DataIC50:  10.8nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244718(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human FAAH after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245031(CHEMBL488708 | N-(6-methoxypyrimidin-4-yl)-4-(3-ph...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244718(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human FAAH preincubated for 40 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244837(CHEMBL461935 | N-(2-chlorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  18.3nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244890(CHEMBL472535 | N-(2-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245065(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrazin-2-yl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245109(CHEMBL488867 | N-(isoxazol-3-yl)-4-(3-phenyl-1,2,4...)
Affinity DataIC50:  25.7nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244992(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyridin-4-yl...)
Affinity DataIC50:  26nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244992(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyridin-4-yl...)
Affinity DataIC50:  26.7nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245031(CHEMBL488708 | N-(6-methoxypyrimidin-4-yl)-4-(3-ph...)
Affinity DataIC50:  28.8nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244837(CHEMBL461935 | N-(2-chlorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  31.7nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244718(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244718(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245110(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(2H-tetrazol-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244774(CHEMBL461380 | N-(2-methoxyphenyl)-4-(3-phenyl-1,2...)
Affinity DataIC50:  47nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  48nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245033(CHEMBL488709 | N-(6-chloropyridazin-3-yl)-4-(3-phe...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245033(CHEMBL488709 | N-(6-chloropyridazin-3-yl)-4-(3-phe...)
Affinity DataIC50:  54nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245029(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(pyrimidin-2-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244990(CHEMBL472188 | N-phenyl-4-(3-m-tolyl-1,2,4-thiadia...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244718(CHEMBL460273 | JNJ-1661010 | N-phenyl-4-(3-phenyl-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245109(CHEMBL488867 | N-(isoxazol-3-yl)-4-(3-phenyl-1,2,4...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244772(CHEMBL461942 | N-(4-methoxyphenyl)-4-(3-phenyl-1,2...)
Affinity DataIC50:  84nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244838(CHEMBL518812 | N-(4-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  91nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244838(CHEMBL518812 | N-(4-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245107(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(4-phenylthia...)
Affinity DataIC50:  113nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244946(4-(3-(4-fluorophenyl)-1,2,4-thiadiazol-5-yl)-N-phe...)
Affinity DataIC50:  117nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244990(CHEMBL472188 | N-phenyl-4-(3-m-tolyl-1,2,4-thiadia...)
Affinity DataIC50:  122nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245067(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-(1H-pyrazol-5...)
Affinity DataIC50:  125nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244889(CHEMBL472534 | N-(3-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  143nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244989(CHEMBL472187 | N-phenyl-4-(3-p-tolyl-1,2,4-thiadia...)
Affinity DataIC50:  147nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244776(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-m-tolylpipera...)
Affinity DataIC50:  148nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244772(CHEMBL461942 | N-(4-methoxyphenyl)-4-(3-phenyl-1,2...)
Affinity DataIC50:  152nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244889(CHEMBL472534 | N-(3-fluorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  152nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244836(CHEMBL461753 | N-(3-chlorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  163nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244774(CHEMBL461380 | N-(2-methoxyphenyl)-4-(3-phenyl-1,2...)
Affinity DataIC50:  173nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245032(CHEMBL528107 | N-(5-cyanopyrimidin-4-yl)-4-(3-phen...)
Affinity DataIC50:  188nMAssay Description:Inhibition of rat FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244776(4-(3-phenyl-1,2,4-thiadiazol-5-yl)-N-m-tolylpipera...)
Affinity DataIC50:  193nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244947(4-(3-(4-chlorophenyl)-1,2,4-thiadiazol-5-yl)-N-phe...)
Affinity DataIC50:  248nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50245032(CHEMBL528107 | N-(5-cyanopyrimidin-4-yl)-4-(3-phen...)
Affinity DataIC50:  253nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50244836(CHEMBL461753 | N-(3-chlorophenyl)-4-(3-phenyl-1,2,...)
Affinity DataIC50:  257nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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