Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50027549
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50273917(CHEMBL462089 | Isolissoclinotoxin B)
Affinity DataIC50:  5.86E+4nMAssay Description:Inhibition of GST fused human Hdm2 assessed as polyubiquitylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50273972(CHEMBL461462 | Lissoclinidine B)
Affinity DataIC50:  5.86E+4nMAssay Description:Inhibition of GST fused human Hdm2 assessed as polyubiquitylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50273919(CHEMBL513108 | Diplamine B)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibition of GST fused human Hdm2 assessed as polyubiquitylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50273918(CHEMBL462090 | N,N-dimethyl-5-methylvaracin)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of GST fused human Hdm2 assessed as polyubiquitylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50240848(2-(3,4-Dimethoxy-5,6,7,8,9-pentathia-benzocyclohep...)
Affinity DataIC50: >2.95E+5nMAssay Description:Inhibition of GST fused human Hdm2 assessed as polyubiquitylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed