Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 3053
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.650nM ΔG°:  -53.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27337(1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-...)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.900nM ΔG°:  -52.5kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27341(8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(piperidin...)
Affinity DataKi:  2.10nM ΔG°:  -50.4kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27341(8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(piperidin...)
Affinity DataKi:  2.30nM ΔG°:  -50.1kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27337(1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-...)
Affinity DataKi:  2.80nM ΔG°:  -49.6kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27343(8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-methylp...)
Affinity DataKi:  2.80nM ΔG°:  -49.6kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27338(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-N-(piper...)
Affinity DataKi:  3.60nM ΔG°:  -49.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27340(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(piper...)
Affinity DataKi:  4.20nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27342(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(4-met...)
Affinity DataKi:  5.20nM ΔG°:  -48.1kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27342(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(4-met...)
Affinity DataKi:  5.90nM ΔG°:  -47.8kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27340(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-6-(piper...)
Affinity DataKi:  6.10nM ΔG°:  -47.7kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27339(9-(4-chlorophenyl)-N-cyclohexyl-8-(2,4-dichlorophe...)
Affinity DataKi:  7.10nM ΔG°:  -47.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Pfizer

LigandPNGBDBM27338(9-(4-chlorophenyl)-8-(2,4-dichlorophenyl)-N-(piper...)
Affinity DataKi:  7.40nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27339(9-(4-chlorophenyl)-N-cyclohexyl-8-(2,4-dichlorophe...)
Affinity DataKi:  12nM ΔG°:  -46.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM27343(8-(2-chlorophenyl)-9-(4-chlorophenyl)-6-(4-methylp...)
Affinity DataKi:  24nM ΔG°:  -44.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed