Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50028022
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255261(CHEMBL479278 | N-(2-aminophenyl)-4-((4-(6-morpholi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255101(CHEMBL519604 | N-(2-aminophenyl)-4-((6-(pyridin-3-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255378(CHEMBL480623 | N-(2-aminophenyl)-4-((4-(thiophen-3...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255262(CHEMBL479279 | N-(2-aminophenyl)-4-((4-(6-(4-methy...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255425(CHEMBL516236 | N-(2-aminophenyl)-4-((4-(4-(2-morph...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255263(CHEMBL480026 | N-(2-aminophenyl)-4-((4-(6-(methylt...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255424(CHEMBL481998 | N-(2-aminophenyl)-4-((4-(4-(morphol...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255917(CHEMBL480923 | N-(2-aminophenyl)-4-((3-(pyridin-3-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255102(CHEMBL481211 | N-(2-aminophenyl)-4-((6-(pyridin-3-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255469(CHEMBL480043 | N-(2-aminophenyl)-4-((4-(4-(2-(dime...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50234080(CHEMBL258813 | N-(2-aminophenyl)-4-(3-(4-(pyridin-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255470(CHEMBL480044 | N-(2-aminophenyl)-4-((4-(3-(2-(dime...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255468(CHEMBL515292 | N-(2-aminophenyl)-4-((4-(3-(2-morph...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255379(CHEMBL520084 | N-(2-aminophenyl)-4-((4-(thiazol-2-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255321(CHEMBL479637 | N-(2-aminophenyl)-4-((4-(6-cyanopyr...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255260(4-((4-amino-6-(pyridin-3-yl)pyrimidin-2-ylamino)me...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255099(4-((2,3'-bipyridin-6-ylamino)methyl)-N-(2-aminophe...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255377(CHEMBL480622 | N-(2-aminophenyl)-4-((4-(pyrazin-2-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255100(CHEMBL481997 | N-(2-aminophenyl)-4-((2-(pyridin-3-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255423(CHEMBL520601 | N-(2-aminophenyl)-4-((4-(3-(hydroxy...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255323(CHEMBL481988 | N-(2-aminophenyl)-4-((4-(6-(2-hydro...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255376(CHEMBL480430 | N-(2-aminophenyl)-4-((4-(6-(morphol...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255322(CHEMBL481795 | N-(2-aminophenyl)-4-((4-(6-(2-(meth...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255146(CHEMBL482002 | N-(2-aminophenyl)-4-((2-(methylthio...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50:  290nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50:  320nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255324(5-(2-(4-(2-aminophenylcarbamoyl)benzylamino)pyrimi...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255916((E)-N-(2-aminophenyl)-3-(4-((4-(pyridin-3-yl)pyrim...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255915(CHEMBL481727 | N-(2-aminophenyl)-4-(4-(pyridin-3-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM24624(CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255857(CHEMBL481556 | N-(2-aminophenyl)-3-((4-(pyridin-3-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255856(2-amino-N-(4-((4-(pyridin-3-yl)pyrimidin-2-ylamino...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255422(4-((4-(1H-pyrazol-5-yl)pyrimidin-2-ylamino)methyl)...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50255855(CHEMBL519601 | N-phenyl-4-((4-(pyridin-3-yl)pyrimi...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed