Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50028180
TargetHistone deacetylase 4(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  9.60nMAssay Description:Inhibition of recombinant HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  36nMAssay Description:Inhibition of recombinant HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataKi:  82nMAssay Description:Inhibition of recombinant HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(pipe...)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(CHEMBL491316 | N-hydroxy-3-(2-phenethyl-1-(2-(pyrr...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248570(3-(1-(3-(dimethylamino)-2,2-dimethylpropyl)-2-phen...)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248375(CHEMBL491688 | N-hydroxy-3-(2-phenethyl-1-(3,4,5-t...)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248475(3-(1-(2-(diethylamino)ethyl)-2-phenethyl-1H-benzo[...)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248314(CHEMBL474746 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248261(CHEMBL475145 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248256(3-(1-(4-(dimethylamino)butyl)-2-phenethyl-1H-benzo...)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248524(3-(1-(3-(1H-imidazol-1-yl)propyl)-2-phenethyl-1H-b...)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248316(CHEMBL515906 | N-hydroxy-3-(2-phenethyl-1H-benzo[d...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248315(3-(2-(benzyloxymethyl)-1-(3-hydroxypropyl)-1H-benz...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM103534(CHEMBL474152 | US10201527, Compound 40 | US1073688...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248431(CHEMBL489125 | N-hydroxy-3-(2-phenethyl-1-propyl-1...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248573(CHEMBL464719 | N-hydroxy-3-(2-phenethyl-1-(3,4,5-t...)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248525(3-(1-(3-(dimethylamino)propyl)-2-phenethyl-1H-benz...)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248473(CHEMBL523646 | N-hydroxy-3-(1-(3-(2-oxopyrrolidin-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248432(CHEMBL521909 | N-hydroxy-3-(1-(3-methoxypropyl)-2-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248376(3-(1-ethyl-2-phenethyl-1H-benzo[d]imidazol-5-yl)-N...)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248474(CHEMBL491490 | N-hydroxy-3-(1-(3-morpholinopropyl)...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247927(CHEMBL489706 | N-hydroxy-3-(2-phenethyl-1-(pyridin...)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM38236(CHEMBL522269 | US10201527, Compound 48 | US1073688...)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248429(CHEMBL489709 | N-hydroxy-3-(1-(2-morpholinoethyl)-...)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248523(CHEMBL489330 | N-hydroxy-3-(2-phenethyl-1-(3-(pyrr...)
Affinity DataIC50:  310nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM38237(CHEMBL491687 | US10201527, Compound 33 | US1073688...)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248312(CHEMBL474151 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50:  530nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248430(3-(1,2-diphenethyl-1H-benzo[d]imidazol-5-yl)-N-hyd...)
Affinity DataIC50:  880nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248257((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247926(3-(1-benzyl-2-phenethyl-1H-benzo[d]imidazol-6-yl)-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248574(CHEMBL464927 | N-hydroxy-2-(1-methyl-2-phenethyl-1...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248260(CHEMBL474547 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248259(CHEMBL474546 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248377(3-(5-(3-(hydroxyamino)-3-oxoprop-1-enyl)-2-pheneth...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248258(3-(2-cyclohexyl-1-(3-hydroxypropyl)-1H-benzo[d]imi...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248572(CHEMBL464718 | N-hydroxy-1-(3-hydroxypropyl)-2-phe...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248571(CHEMBL461173 | N-hydroxy-3-(1-(3-hydroxypropyl)-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247928(CHEMBL489902 | N-(2-aminophenyl)-3-(2-phenethyl-1-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed