Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50038915
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046261(2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...)
Affinity DataIC50:  41nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  50nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298107(3-(4-Hydroxy-phenyl)-2-(4,4,4-trifluoro-3-mercapto...)
Affinity DataIC50:  80nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298107(3-(4-Hydroxy-phenyl)-2-(4,4,4-trifluoro-3-mercapto...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298111(3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluor...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50:  300nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298111(3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluor...)
Affinity DataIC50:  430nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50:  580nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin [1-24](Sus scrofa)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298110(2-(4,4,5,5,5-Pentafluoro-3-mercapto-pentanoylamino...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046258(3-(4-Hydroxy-phenyl)-2-[2-(3-mercapto-5-methyl-hex...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298111(3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluor...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298108(3-(4-Fluoro-phenyl)-2-(4,4,4-trifluoro-3-mercapto-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046261(2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50046261(2-(3-Mercapto-5-methyl-hexanoylamino)-3-phenyl-pro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298107(3-(4-Hydroxy-phenyl)-2-(4,4,4-trifluoro-3-mercapto...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed