Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 50032652
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332752((2R)-6,8-dichloro-7-(2-methylpropoxy)-2-(trifluoro...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332761(7-tert-butyl-6-chloro-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332769((R)-6-chloro-7-propyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50026234(CHEMBL1630239)
Affinity DataIC50: <6nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332771((R)-6-chloro-7-isobutyl-2-(trifluoromethyl)-2H-chr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332773((R)-6-chloro-7-(isobutylthio)-2-(trifluoromethyl)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331887((2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331873(5,6-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332765(6-chloro-7-(isobutylthio)-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332763(6-chloro-7-isobutyl-2-(trifluoromethyl)-2H-chromen...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50026213(CHEMBL1630240)
Affinity DataIC50: <21nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50026214(CHEMBL1630241)
Affinity DataIC50: <28nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332752((2R)-6,8-dichloro-7-(2-methylpropoxy)-2-(trifluoro...)
Affinity DataIC50: <28nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332753(6,8-dichloro-7-(cyclohexylmethoxy)-2-(trifluoromet...)
Affinity DataIC50: <34nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332759(6-chloro-7-(2-ethylbutoxy)-2-(trifluoromethyl)-2H-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332768((2S)-7-tert-butyl-6-chloro-2-(trifluoromethyl)-2H-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332777((R)-6-chloro-7-isopentyl-2-(trifluoromethyl)-2H-ch...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332766(6-chloro-7-(isobutyl(methyl)amino)-2-(trifluoromet...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332775((R)-6-chloro-7-(isobutyl(methyl)amino)-2-(trifluor...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332764(6-chloro-7-isopentyl-2-(trifluoromethyl)-2H-chrome...)
Affinity DataIC50:  94nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332744(6-chloro-5-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50026214(CHEMBL1630241)
Affinity DataIC50: <140nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332770((S)-6-chloro-7-propyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50026234(CHEMBL1630239)
Affinity DataIC50: <140nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50026213(CHEMBL1630240)
Affinity DataIC50: <140nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332774((S)-6-chloro-7-(isobutylthio)-2-(trifluoromethyl)-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332762(6-chloro-7-propyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332760(6-chloro-7-isopropyl-2-(trifluoromethyl)-2H-chrome...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332749(6-chloro-5-(phenylthio)-2-(trifluoromethyl)-2H-chr...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332771((R)-6-chloro-7-isobutyl-2-(trifluoromethyl)-2H-chr...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332751(6-chloro-5-o-tolyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  370nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332769((R)-6-chloro-7-propyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332748(6-chloro-5-phenoxy-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331887((2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  690nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331873(5,6-dichloro-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50:  690nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332776((S)-6-chloro-7-(isobutyl(methyl)amino)-2-(trifluor...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332772((S)-6-chloro-7-isobutyl-2-(trifluoromethyl)-2H-chr...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332768((2S)-7-tert-butyl-6-chloro-2-(trifluoromethyl)-2H-...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332778((S)-6-chloro-7-isopentyl-2-(trifluoromethyl)-2H-ch...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332746(5-amino-6-chloro-2-(trifluoromethyl)-2H-chromene-3...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332777((R)-6-chloro-7-isopentyl-2-(trifluoromethyl)-2H-ch...)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332770((S)-6-chloro-7-propyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332751(6-chloro-5-o-tolyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332773((R)-6-chloro-7-(isobutylthio)-2-(trifluoromethyl)-...)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332753(6,8-dichloro-7-(cyclohexylmethoxy)-2-(trifluoromet...)
Affinity DataIC50:  3.79E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332750(6-chloro-5-phenyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  4.64E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332767((R)-7-tert-butyl-6-chloro-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  5.15E+3nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332744(6-chloro-5-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  7.44E+3nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332775((R)-6-chloro-7-(isobutyl(methyl)amino)-2-(trifluor...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of human COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332754(6-chloro-7-((ethyl(methyl)amino)methyl)-2-(trifluo...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of human COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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