Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50032384
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328264(5-(2-chlorophenyl)-3-isopropyl-7-nitro-2,10-dihydr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  16nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328279(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  17nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328267(5-(2-chlorophenyl)-7-nitro-3-(1H-pyrrol-2-yl)-2,10...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328280(CHEMBL1258022 | N-(5-(2-chlorophenyl)-2,10-dihydro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)
Affinity DataIC50:  33nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  34nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50:  35nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)
Affinity DataIC50:  38nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  39nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328274(7-fluoro-5-(2-fluorophenyl)-3-methyl-2,10-dihydrob...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328281(CHEMBL1258141 | N'-[5-(2-chlorophenyl)-2,10-dihydr...)
Affinity DataIC50:  46nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328269(5-(2-chlorophenyl)-7-nitro-3-(pyridin-4-yl)-2,10-d...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328272(5-(2-fluorophenyl)-3-methyl-2,10-dihydrobenzo[e]py...)
Affinity DataIC50:  64nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328260(5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyr...)
Affinity DataIC50:  70nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50:  72nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  88nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328273(7-fluoro-3-methyl-5-phenyl-2,10-dihydrobenzo[e]pyr...)
Affinity DataIC50:  93nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328271(5-(2-chlorophenyl)-3-methyl-2,10-dihydrobenzo[e]py...)
Affinity DataIC50:  105nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328270(3-methyl-5-phenyl-2,10-dihydrobenzo[e]pyrazolo[4,3...)
Affinity DataIC50:  115nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  150nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)
Affinity DataIC50:  180nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328277(7-chloro-5-(2-fluorophenyl)-2,10-dihydrobenzo[e]py...)
Affinity DataIC50:  190nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328265(5-(2-chlorophenyl)-7-nitro-3-phenyl-2,10-dihydrobe...)
Affinity DataIC50:  210nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328262(5-(2-chlorophenyl)-7-nitro-3-(trifluoromethyl)-2,1...)
Affinity DataIC50:  232nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328261((5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]py...)
Affinity DataIC50:  238nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328263(5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyr...)
Affinity DataIC50:  258nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328268(5-(2-chlorophenyl)-7-nitro-3-(pyridin-3-yl)-2,10-d...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328278(5-(2-chlorophenyl)-7-methoxy-2,10-dihydrobenzo[e]p...)
Affinity DataIC50:  320nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328276(7-chloro-5-(2-chlorophenyl)-2,10-dihydrobenzo[e]py...)
Affinity DataIC50:  440nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328275(7-chloro-5-phenyl-2,10-dihydrobenzo[e]pyrazolo[4,3...)
Affinity DataIC50:  490nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)
Affinity DataIC50:  726nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328258(CHEMBL1257912 | N-(5-(2-chlorophenyl)-2,10-dihydro...)
Affinity DataIC50:  930nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  989nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328257(5-(2-chlorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  1.84E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328259(6-(thiophen-2-yl)-4-(trifluoromethyl)-1H-pyrazolo[...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328266(5-(2-chlorophenyl)-7-nitro-3-phenethyl-2,10-dihydr...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CDK2-cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328256(5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50328255(5-(2-chlorophenyl)-3-methyl-7-nitro-2,10-dihydrobe...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed