Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50039392
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337137(2-((2-methoxy-4-(4-(pyrrolidin-1-yl)piperidine-1-c...)
Affinity DataIC50:  130nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataIC50:  190nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337139(11-ethyl-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  200nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337141(11-cyclopentyl-2-((2-methoxy-4-(4-methylpiperazin-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337131(2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperid...)
Affinity DataIC50:  200nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337130(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)-5,11...)
Affinity DataIC50:  230nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337140(11-isopropyl-2-((2-methoxy-4-(4-methylpiperazin-1-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337138(4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...)
Affinity DataIC50:  240nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337128(2-((4-(4-hydroxypiperidin-1-yl)-2-methoxyphenyl)am...)
Affinity DataIC50:  240nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337134(2-((2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl)ami...)
Affinity DataIC50:  240nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337132(2-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)ami...)
Affinity DataIC50:  260nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337129(2-((2-methoxy-4-morpholinophenyl)amino)-5,11-dimet...)
Affinity DataIC50:  260nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337133(5,11-dimethyl-2-((2-methyl-4-(4-methylpiperazin-1-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337135(4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...)
Affinity DataIC50:  310nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337136(4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...)
Affinity DataIC50:  320nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337144(8-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337143(9-fluoro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337142(2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)ami...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337145(9-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase DCLK1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to DCAMKL1 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd:  440nMAssay Description:Binding affinity to TNK2 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase DCLK2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd:  10nMAssay Description:Binding affinity to DCAMKL2 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd:  450nMAssay Description:Binding affinity to GAK by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TNK1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337127(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd:  29nMAssay Description:Binding affinity to TNK1 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd: >670nMAssay Description:Binding affinity to ERK5 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed