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Found 12 Enz. Inhib. hit(s) with all data for entry = 8343
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataKi:  1.04E+4nM IC50:  1.88E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50049707((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...)
Affinity DataKi:  1.73E+4nM IC50:  2.13E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM237182(Ceftizoxime)
Affinity DataKi:  2.28E+4nM IC50:  3.97E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50390999(CEFOPERAZONE)
Affinity DataKi:  2.87E+4nM IC50:  4.84E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal glutathione S-transferase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataKi:  3.24E+4nM IC50:  5.64E+4nMpH: 6.5Assay Description:Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione peroxidase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50422689(640/359 | CEFUROXIME)
Affinity DataKi:  3.27E+4nM IC50:  4.43E+4nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione peroxidase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50049707((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...)
Affinity DataKi:  3.41E+4nM IC50:  4.86E+4nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal glutathione S-transferase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50049707((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...)
Affinity DataKi:  3.54E+4nM IC50:  6.18E+4nMpH: 6.5Assay Description:Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione peroxidase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM237182(Ceftizoxime)
Affinity DataKi:  1.21E+5nM IC50:  1.86E+5nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal glutathione S-transferase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM237182(Ceftizoxime)
Affinity DataKi:  1.65E+5nM IC50:  2.78E+5nMpH: 6.5Assay Description:Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione peroxidase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50390999(CEFOPERAZONE)
Affinity DataKi:  2.45E+5nM IC50:  3.13E+5nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal glutathione S-transferase 1(Homo sapiens (Human))
Ondokuz Mayis University

LigandPNGBDBM50390999(CEFOPERAZONE)
Affinity DataKi:  2.67E+5nM IC50:  4.84E+5nMpH: 6.5Assay Description:Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed