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Found 196 Enz. Inhib. hit(s) with all data for entry = 50040583
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396463(CHEMBL2170611)
Affinity DataIC50:  5nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396469(CHEMBL2170610)
Affinity DataIC50:  6nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396471(CHEMBL2170608)
Affinity DataIC50:  10nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396470(CHEMBL2170609)
Affinity DataIC50:  11nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396436(CHEMBL2170615)
Affinity DataIC50:  14nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396435(CHEMBL2170617)
Affinity DataIC50:  14nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396465(CHEMBL2169894)
Affinity DataIC50:  15nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396443(CHEMBL2170632)
Affinity DataIC50:  15nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396464(CHEMBL2170603)
Affinity DataIC50:  15nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396472(CHEMBL2170607)
Affinity DataIC50:  16nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396439(CHEMBL2170637)
Affinity DataIC50:  18nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396440(CHEMBL2170636)
Affinity DataIC50:  18nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396434(CHEMBL2170618)
Affinity DataIC50:  18nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396441(CHEMBL2170635)
Affinity DataIC50:  18nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396468(CHEMBL2170612)
Affinity DataIC50:  19nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396437(CHEMBL2170639)
Affinity DataIC50:  19nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396449(CHEMBL2170628)
Affinity DataIC50:  21nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396466(CHEMBL2170614)
Affinity DataIC50:  22nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396436(CHEMBL2170615)
Affinity DataIC50:  23nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396446(CHEMBL2170629)
Affinity DataIC50:  24nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396437(CHEMBL2170639)
Affinity DataIC50:  25nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396438(CHEMBL2170638)
Affinity DataIC50:  26nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396447(CHEMBL2170616)
Affinity DataIC50:  27nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396462(SABIPORIDE)
Affinity DataIC50:  28nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396463(CHEMBL2170611)
Affinity DataIC50:  28nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396473(CHEMBL2170606)
Affinity DataIC50:  28nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396475(CHEMBL2170604)
Affinity DataIC50:  29nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396467(CHEMBL2170613)
Affinity DataIC50:  29nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396479(CHEMBL2170622)
Affinity DataIC50:  30nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396470(CHEMBL2170609)
Affinity DataIC50:  31nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396469(CHEMBL2170610)
Affinity DataIC50:  31nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396440(CHEMBL2170636)
Affinity DataIC50:  32nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396451(CHEMBL2170626)
Affinity DataIC50:  33nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396445(CHEMBL2170630)
Affinity DataIC50:  35nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396461(CHEMBL2170650)
Affinity DataIC50:  36nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396478(CHEMBL2170623)
Affinity DataIC50:  36nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396438(CHEMBL2170638)
Affinity DataIC50:  36nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396459(CHEMBL2170640)
Affinity DataIC50:  41nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396458(CHEMBL2170641)
Affinity DataIC50:  45nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396476(CHEMBL2170625)
Affinity DataIC50:  47nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396471(CHEMBL2170608)
Affinity DataIC50:  48nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396480(CHEMBL2170621)
Affinity DataIC50:  50nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396472(CHEMBL2170607)
Affinity DataIC50:  50nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396442(CHEMBL2170633)
Affinity DataIC50:  50nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396481(CHEMBL2170620)
Affinity DataIC50:  52nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396464(CHEMBL2170603)
Affinity DataIC50:  56nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396448(CHEMBL2170634)
Affinity DataIC50:  58nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396441(CHEMBL2170635)
Affinity DataIC50:  60nMAssay Description:Inhibiton of CYP2C19 in human liver microsomes using 7-ethoxy-3-cyanocoumarin as substrate after 45 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396442(CHEMBL2170633)
Affinity DataIC50:  60nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50396444(CHEMBL2170631)
Affinity DataIC50:  61nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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