Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50040185
TargetCytochrome P450 2D6(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390599(CHEMBL2069579)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390608(CHEMBL2069588)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390599(CHEMBL2069579)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390599(CHEMBL2069579)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390608(CHEMBL2069588)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390582(CHEMBL2069487)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390583(CHEMBL2069488)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390584(CHEMBL2069489)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390585(CHEMBL2069490)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390586(CHEMBL2069491)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390587(CHEMBL2069492)
Affinity DataEC50:  6.60E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390588(CHEMBL2069493)
Affinity DataEC50:  2.50E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390589(CHEMBL2069494)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390590(CHEMBL2069495)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390591(CHEMBL2069496)
Affinity DataEC50:  760nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390592(CHEMBL2069497)
Affinity DataEC50:  830nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390593(CHEMBL2069573)
Affinity DataEC50:  93nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390594(CHEMBL2069574)
Affinity DataEC50:  360nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390595(CHEMBL2069575)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390596(CHEMBL2069576)
Affinity DataEC50:  89nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390597(CHEMBL2069577)
Affinity DataEC50:  53nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390598(CHEMBL2069578)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390599(CHEMBL2069579)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390600(CHEMBL2069580)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390601(CHEMBL2069581)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390602(CHEMBL2069582)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390603(CHEMBL2069583)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390604(CHEMBL2069584)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390605(CHEMBL2069585)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390606(CHEMBL2069586)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390607(CHEMBL2069587)
Affinity DataEC50:  640nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390608(CHEMBL2069588)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390609(CHEMBL2069589)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390610(CHEMBL2069590)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390594(CHEMBL2069574)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390595(CHEMBL2069575)
Affinity DataEC50:  970nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390597(CHEMBL2069577)
Affinity DataEC50:  810nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390598(CHEMBL2069578)
Affinity DataEC50:  980nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390599(CHEMBL2069579)
Affinity DataEC50:  480nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390608(CHEMBL2069588)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390596(CHEMBL2069576)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390611(CHEMBL2069498)
Affinity DataEC50:  780nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390577(CHEMBL2069482)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at mouse GPR142 assessed as inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390581(CHEMBL2069486)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390580(CHEMBL2069485)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390579(CHEMBL2069484)
Affinity DataEC50: >3.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390593(CHEMBL2069573)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390577(CHEMBL2069482)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50390578(CHEMBL2069483)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed