Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50042513
TargetNEDD8-activating enzyme E1 regulatory subunit(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of NAE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50:  10nMAssay Description:Inhibition of NAE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427031(CHEMBL2322197)
Affinity DataIC50:  800nMAssay Description:Inhibition of NAE (unknown origin)-catalyzed NEDD8-Ubcl2 intermediate formation by densitometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin-like modifier-activating enzyme 6(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50:  920nMAssay Description:Inhibition of UBA6 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin-like modifier-activating enzyme 6(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of UBA6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSUMO-activating enzyme subunit 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant SAE1(unknown origin)-mediated SUMOylation of RanGAP1-C2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSUMO-activating enzyme subunit 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50242188(6-(8'Z-pentadecenyl)-salicylicacid | 6-[8'(Z)-pent...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant SAE1(unknown origin)-mediated SUMOylation of RanGAP1-C2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin-like modifier-activating enzyme 7(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of UBA7 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427032(6,6''-Biapigenin | CHEMBL2322196)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of NAE (unknown origin) assessed as decrease in NEDD8-Ubcl2 formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSUMO-activating enzyme subunit 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of SAE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSUMO-activating enzyme subunit 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of SAE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ATG7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSUMO-activating enzyme subunit 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427033(CHEMBL2322195 | Kerriamycin B)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of recombinant His-tagged SAE1(unknown origin)-mediated SUMOylation of RanGAP1-C2 by immunoblotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427032(6,6''-Biapigenin | CHEMBL2322196)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of NAE (unknown origin)-catalyzed transthiolation of NEDD8 from NAE to Ubc12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of ATG7 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSUMO-activating enzyme subunit 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50322422(CHEMBL1173445 | Largazole)
Affinity DataIC50:  4.50E+5nMAssay Description:Inhibition of human SAE by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed