Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50043103
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataKi:  0.0100nMAssay Description:Antagonist activity at human CGRP receptorMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50268484((R)-4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-...)
Affinity DataKi:  0.0130nMAssay Description:Antagonist activity at human CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50356282(CHEMBL1910936)
Affinity DataKi:  0.0210nMAssay Description:Antagonist activity at human CGRP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50436107(CHEMBL2397415)
Affinity DataKi:  0.0230nMAssay Description:Displacement of [125I]-CGRP from CGRP receptor in human SK-N-MC cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50224431(CHEMBL236593 | MK-0974 | N-[(3R,6S)-6-(2,3-difluor...)
Affinity DataKi:  0.770nMAssay Description:Antagonist activity at human CGRP receptorMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50436107(CHEMBL2397415)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) expressed in baculovirus-infected insect cell microsomes assessed as 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7-m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50436107(CHEMBL2397415)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) expressed in baculovirus-infected insect cell microsomes assessed as 3-cyano-7-ethoxycoumarin conversion to 7-h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50436107(CHEMBL2397415)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) expressed in baculovirus-infected insect cell microsomes assessed as 3-cyano-7-ethoxycoumarin conversion to 7-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50436107(CHEMBL2397415)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) expressed in baculovirus-infected insect cell microsomes assessed as 7-methoxy-4-trifluoromethylcoumarin conver...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed