Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50045084
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50440531(CHEMBL2426168)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of BLM helicase (unknown origin) binding to DNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50440531(CHEMBL2426168)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of WRN helicase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDouble-strand break repair protein MRE11(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50044627(Mirin)
Affinity DataIC50:  1.20E+4nMAssay Description:In vitro inhibition of purified recombinant Mre11 exonuclease activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50044626(CHEMBL1374426)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of WRN helicase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRecQ-like DNA helicase BLM(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50440531(CHEMBL2426168)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of BLM helicase (unknown origin) assessed as branch migration activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDouble-strand break repair protein MRE11(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50044627(Mirin)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of Mre11 exonuclease activity (unknown origin) in cell free extractsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA repair and recombination protein RAD54-like(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50447758(CHEBI:9287 | NSC-45383 | Nigrin | Rufocromomycin |...)
Affinity DataEC50:  1.65E+4nMAssay Description:Inhibition of RAD54 (unknown origin) ATPase activity assessed as generation of reactive oxygen speciesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell cycle checkpoint protein RAD1(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50424495(CHEMBL2316726)
Affinity DataEC50:  4.40E+4nMAssay Description:Inhibition of RAD1 (unknown origin) binding to ssDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell cycle checkpoint protein RAD1(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50044628(CHEBI:4286 | CHEMBL1162148)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of RAD1 (unknown origin) binding to ssDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell cycle checkpoint protein RAD1(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50044628(CHEBI:4286 | CHEMBL1162148)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to RAD1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell cycle checkpoint protein RAD1(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM39120(3-chloranyl-1-(3,4-dichlorophenyl)-4-morpholin-4-y...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of RAD1 (unknown origin) binding to ssDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell cycle checkpoint protein RAD1(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataKd:  5.60E+3nMAssay Description:Binding affinity to RAD1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell cycle checkpoint protein RAD1(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM48804(3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of RAD1 (unknown origin) binding to ssDNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed