Affinity DataIC50: 60nMAssay Description:Inhibition of of rat TREK1 expressed in CHO cells assessed as reversible current depressionMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of of TREK1 (unknown origin) expressed in whole COS7 cells assessed as reduction in channel currents in presence of 10 uM arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of of human TREK1 expressed in HEK293 cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of of human TREK1 expressed in whole COS cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of of human TREK1 expressed in whole COS cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of of human TREK1 expressed in whole COS cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of of human TREK1 expressed in HEK293 cells assessed as reversible current depressionMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of of human TREK1 expressed in whole COS cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of of TASK1 (unknown origin) expressed in CHO cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of of human TREK1 expressed in whole COS cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of of human TREK1 expressed in CHO cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of of TREK2 (unknown origin) expressed in HEK293 cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of of human TREK1 expressed in tsA201 cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of of human TREK1 expressed in HEK293 cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of of human TREK1 expressed in tsA201 cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of of human TREK1 expressed in whole COS cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of of human TREK1 expressed in oocytes assessed as reversible current depressionMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of of TREK2 (unknown origin) expressed in oocytes assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.73E+4nMAssay Description:Inhibition of of TASK1 (unknown origin) expressed in CHO cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+5nMAssay Description:Inhibition of of human TREK1 expressed in CHO cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+5nMAssay Description:Inhibition of of human TREK1 expressed in HEK293 cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at +50 mV relative to controlMore data for this Ligand-Target Pair
Affinity DataEC50: 2.13E+5nMAssay Description:Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currentsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.39E+5nMAssay Description:Activation of TREK1 (unknown origin) expressed in COS7 cells assessed as increase in whole cell currents at +50 mV relative to controlMore data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+4nMAssay Description:Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currentsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+4nMAssay Description:Activation of TRAAK (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currentsMore data for this Ligand-Target Pair
Affinity DataEC50: 9.70E+3nMAssay Description:Activation of TREK1 (unknown origin) expressed in HEK293 cells assessed as increase in current density relative to controlMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:Activation of TREK2 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currentsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+5nMAssay Description:Activation of TREK1 (unknown origin) expressed in COS7 cells assessed as increase in whole cell currents at +50 mV relative to controlMore data for this Ligand-Target Pair
Affinity DataEC50: 1.25E+5nMAssay Description:Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currentsMore data for this Ligand-Target Pair