Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 7618
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)
Affinity DataIC50:  27nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)
Affinity DataIC50:  34nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)
Affinity DataIC50:  74nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206286((S)-N1-(3-(1H-indol-3-yl)-1-((4-iodophenyl)amino)-...)
Affinity DataIC50:  78nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206285((S)-N1-(1-((4-bromophenyl)amino)-3-(1H-indol-3-yl)...)
Affinity DataIC50:  96nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  131nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206284((S)-N1-(1-((4-chlorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50:  150nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)
Affinity DataIC50:  168nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206281((S)-N1-(1-((3-bromophenyl)amino)-3-(1H-indol-3-yl)...)
Affinity DataIC50:  189nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206283((S)-N1-(1-((4-fluorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50:  202nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)
Affinity DataIC50:  219nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206278((S)-N1-(3-(1H-indol-3-yl)-1-((naphthalen-1-ylmethy...)
Affinity DataIC50:  225nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206267((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(propylamino)pro...)
Affinity DataIC50:  227nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206279((S)-N1-(1-((3-fluorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50:  234nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206277((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenethylamino)...)
Affinity DataIC50:  301nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206289((S)-N1-(1-((4-ethoxyphenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50:  335nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206276((S)-N1-(1-(benzylamino)-3-(1H-indol-3-yl)-1-oxopro...)
Affinity DataIC50:  346nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)
Affinity DataIC50:  353nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206280((S)-N1-(1-((3-chlorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50:  360nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206275((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenylamino)pro...)
Affinity DataIC50:  361nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206288((S)-N1-(3-(1H-indol-3-yl)-1-((4-methoxyphenyl)amin...)
Affinity DataIC50:  413nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206274((S)-N1-(1-(cyclohexylamino)-3-(1H-indol-3-yl)-1-ox...)
Affinity DataIC50:  416nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206282((S)-N1-(3-(1H-indol-3-yl)-1-((3-methoxyphenyl)amin...)
Affinity DataIC50:  435nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206272((S)-N1-(1-(tert-butylamino)-3-(1H-indol-3-yl)-1-ox...)
Affinity DataIC50:  504nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206271((S)-N1-(3-(1H-indol-3-yl)-1-(isobutylamino)-1-oxop...)
Affinity DataIC50:  527nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206273((S)-N1-(1-(cyclopropylamino)-3-(1H-indol-3-yl)-1-o...)
Affinity DataIC50:  683nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206290((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-((4-(trifluorome...)
Affinity DataIC50:  1.29E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206268((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(propylamino)pro...)
Affinity DataIC50:  1.65E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206269((S)-N1-(1-(butylamino)-3-(1H-indol-3-yl)-1-oxoprop...)
Affinity DataIC50:  1.74E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)
Affinity DataIC50:  3.50E+3nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)
Affinity DataIC50:  5.50E+3nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Shandong University

LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)
Affinity DataIC50:  9.90E+3nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Shandong University

LigandPNGBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)
Affinity DataIC50:  2.50E+4nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206270((S)-N1-(1-(dodecylamino)-3-(1H-indol-3-yl)-1-oxopr...)
Affinity DataIC50: >2.50E+4nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Shandong University

LigandPNGBDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)
Affinity DataIC50: >1.00E+5nMAssay Description:To further ascertain HDAC isoform selectivity of 12m, we conducted enzymatic inhibitory assays against HDAC1 (class I), HDAC8 (class I), HDAC6 (class...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed