Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50035699
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
TargetThymidylate synthase(Escherichia coli)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022390(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pter...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against thymidylate synthase of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory activity against GAR transformylase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibitory activity against AICAR formyltransferase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022387(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyrido...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022385(2-{4-[2-(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
Sri International

Curated by ChEMBL
LigandPNGBDBM50022386(2-{4-[2-(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pyri...)
Affinity DataIC50:  3.40E+5nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed