Compile Data Set for Download or QSAR
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Found 37 Enz. Inhib. hit(s) with all data for entry = 50006716
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50:  18nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  26nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50:  43nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  65nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052672(Adamantane-1-carboxylic acid (R)-1-pyridin-4-yl-et...)
Affinity DataIC50:  74nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052666(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-3-...)
Affinity DataIC50:  92nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052667(Adamantane-1-carboxylic acid (R)-1-pyridin-3-yl-et...)
Affinity DataIC50:  150nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052664(Adamantane-1-carboxylic acid ((S)-1-pyridin-4-yl-e...)
Affinity DataIC50:  210nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50:  230nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052672(Adamantane-1-carboxylic acid (R)-1-pyridin-4-yl-et...)
Affinity DataIC50:  340nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052666(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-3-...)
Affinity DataIC50:  390nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052674(Adamantane-1-carboxylic acid ((R)-1-pyridin-4-yl-e...)
Affinity DataIC50:  430nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052670(Adamantane-1-carboxylic acid pyridin-3-ylmethyl es...)
Affinity DataIC50:  460nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052667(Adamantane-1-carboxylic acid (R)-1-pyridin-3-yl-et...)
Affinity DataIC50:  580nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052671(Adamantane-1-carboxylic acid pyridin-4-ylmethyl es...)
Affinity DataIC50:  580nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052664(Adamantane-1-carboxylic acid ((S)-1-pyridin-4-yl-e...)
Affinity DataIC50:  820nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50:  840nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052670(Adamantane-1-carboxylic acid pyridin-3-ylmethyl es...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052675(Adamantane-1-carboxylic acid (pyridin-4-ylmethyl)-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052675(Adamantane-1-carboxylic acid (pyridin-4-ylmethyl)-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052674(Adamantane-1-carboxylic acid ((R)-1-pyridin-4-yl-e...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052673(Adamantane-1-carboxylic acid (S)-1-pyridin-3-yl-et...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052668(Adamantane-1-carboxylic acid (S)-1-pyridin-4-yl-et...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052675(Adamantane-1-carboxylic acid (pyridin-4-ylmethyl)-...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052670(Adamantane-1-carboxylic acid pyridin-3-ylmethyl es...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052672(Adamantane-1-carboxylic acid (R)-1-pyridin-4-yl-et...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of C17,20-lyase enzyme, cytochrome P450 17A1 in Human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052669(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-4-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052667(Adamantane-1-carboxylic acid (R)-1-pyridin-3-yl-et...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052666(Adamantane-1-carboxylic acid 1-methyl-1-pyridin-3-...)
Affinity DataIC50:  5.10E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Cancer Research Campaign Centre For Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase enzyme, cytochrome P450 17A1 of human testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed