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Found 19 Enz. Inhib. hit(s) with all data for entry = 1257
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)
Affinity DataIC50:  0.770nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  44nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10469(Bis-THA inhibitor 1c | Bis-THA inhibitor 8 | CHEMB...)
Affinity DataIC50:  190nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10475(N-(8-phenyloctyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  210nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10474(N-(7-phenylheptyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50:  390nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  440nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10472(N-(5-phenylpentyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50:  520nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  590nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10473(N-(6-phenylhexyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  610nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10473(N-(6-phenylhexyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  810nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10474(N-(7-phenylheptyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50:  1.00E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10471(N-(4-phenylbutyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10472(N-(5-phenylpentyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10475(N-(8-phenyloctyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  2.40E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10476(N-(9-phenylnonyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  9.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10477(N-(10-phenyldecyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50:  9.40E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10476(N-(9-phenylnonyl)-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50:  2.00E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10477(N-(10-phenyldecyl)-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50:  2.70E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed