Compile Data Set for Download or QSAR
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Found 60 Enz. Inhib. hit(s) with all data for entry = 50007357
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50450532(CHEMBL2308105)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86701(3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...)
Affinity DataKi:  9nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061877(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3....)
Affinity DataKi:  9.70nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061877(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3....)
Affinity DataKi:  11.2nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86701(3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061884(8-Allyl-3-[bis-(4-fluoro-phenyl)-methoxy]-8-aza-bi...)
Affinity DataKi:  14nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50450529(CHEMBL3084934)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061885(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-butyl-8-aza-bi...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061884(8-Allyl-3-[bis-(4-fluoro-phenyl)-methoxy]-8-aza-bi...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061881(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-cyclopropylmet...)
Affinity DataKi:  32.4nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50450532(CHEMBL2308105)
Affinity DataKi:  39nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061889(3-[2,2-Bis-(4-fluoro-phenyl)-ethyl]-8-(3-phenyl-pr...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061880(1-(2-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicy...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061886(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-[2-(4'-nitro-b...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061876(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-[3-(4-fluoro-p...)
Affinity DataKi:  60.7nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM86701(3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicy...)
Affinity DataKi:  71nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061878((E)-1-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bic...)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061878((E)-1-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bic...)
Affinity DataKi:  86.4nMAssay Description:Compound is evaluated for binding to Serotonin transporter using [3H]-Citalopram as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061878((E)-1-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bic...)
Affinity DataKi:  86.4nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061878((E)-1-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bic...)
Affinity DataKi:  86.4nMAssay Description:Compound was evaluated for binding to Norepinephrine Transporter (NET) using [3H]-desmethylimipramine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061878((E)-1-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bic...)
Affinity DataKi:  86.4nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061883(3-[Bis-(4-fluoro-phenyl)-methoxy]-8,8-dimethyl-8-a...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061883(3-[Bis-(4-fluoro-phenyl)-methoxy]-8,8-dimethyl-8-a...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061883(3-[Bis-(4-fluoro-phenyl)-methoxy]-8,8-dimethyl-8-a...)
Affinity DataKi:  108nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061884(8-Allyl-3-[bis-(4-fluoro-phenyl)-methoxy]-8-aza-bi...)
Affinity DataKi:  126nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061881(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-cyclopropylmet...)
Affinity DataKi:  136nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061889(3-[2,2-Bis-(4-fluoro-phenyl)-ethyl]-8-(3-phenyl-pr...)
Affinity DataKi:  136nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061877(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3....)
Affinity DataKi:  156nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061881(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-cyclopropylmet...)
Affinity DataKi:  180nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  200nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061889(3-[2,2-Bis-(4-fluoro-phenyl)-ethyl]-8-(3-phenyl-pr...)
Affinity DataKi:  230nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061885(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-butyl-8-aza-bi...)
Affinity DataKi:  251nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  290nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061885(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-butyl-8-aza-bi...)
Affinity DataKi:  370nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061889(3-[2,2-Bis-(4-fluoro-phenyl)-ethyl]-8-(3-phenyl-pr...)
Affinity DataKi:  375nMAssay Description:Compound is evaluated for binding to Serotonin transporter using [3H]-Citalopram as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50450532(CHEMBL2308105)
Affinity DataKi:  483nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061882(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-(4-fluoro-benz...)
Affinity DataKi:  611nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061875(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-{2-[bis-(4-flu...)
Affinity DataKi:  634nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50450529(CHEMBL3084934)
Affinity DataKi:  650nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  773nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 sites of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061881(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-cyclopropylmet...)
Affinity DataKi:  1.19E+3nMAssay Description:Compound is evaluated for binding to Serotonin transporter using [3H]-Citalopram as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061880(1-(2-{3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicy...)
Affinity DataKi:  1.20E+3nMAssay Description:In vitro inhibition of dopamine uptake in rat tissue, was determined using [3H]-DAU as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061885(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-butyl-8-aza-bi...)
Affinity DataKi:  1.33E+3nMAssay Description:Compound was evaluated for binding to Norepinephrine Transporter (NET) using [3H]-desmethylimipramine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061884(8-Allyl-3-[bis-(4-fluoro-phenyl)-methoxy]-8-aza-bi...)
Affinity DataKi:  1.45E+3nMAssay Description:Compound is evaluated for binding to Serotonin transporter using [3H]-Citalopram as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061885(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-butyl-8-aza-bi...)
Affinity DataKi:  1.73E+3nMAssay Description:Compound is evaluated for binding to Serotonin transporter using [3H]-Citalopram as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061887(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3....)
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of [3H]-WIN- 35, 428 from the dopamine transporter in rat caudate putamen.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061879(8-Benzyl-3-[2,2-bis-(4-fluoro-phenyl)-ethyl]-8-aza...)
Affinity DataKi:  2.08E+3nMAssay Description:Compound was evaluated for binding to Norepinephrine Transporter (NET) using [3H]-desmethylimipramine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50061877(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-aza-bicyclo[3....)
Affinity DataKi:  2.10E+3nMAssay Description:Compound is evaluated for binding to Serotonin transporter using [3H]-Citalopram as radioligand in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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