Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM312186
Substrate
n/a
Meas. Tech.
Receptor Assay
Ki
1.67±0.16 nM
Citation
 McCurdy, CR; Mesangeau, C; Chin, FT; James, ML; Shen, B; Gambhir, S Highly selective sigma receptor radioligands US Patent  US9604926 Publication Date 3/28/2017 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_MOUSE | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
n/a
Mol. Mass.:
20818.69
Organism:
Mus musculus (Mouse)
Description:
Q8VD00
Residue:
176
Sequence:
MGALAARRCVEWLLGLYFVSHIPITLFIDLQAVLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLLCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAAHTITTLIPILYTLLFEDFSKAVAFKGQRPESFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM312186
Synonyms:
US9604926, Compound CM-322 | US9724435, Compound CM-322
Type:
Small organic molecule
Emp. Form.:
C27H28F2N4O
Mol. Mass.:
462.5342
SMILES:
Fc1ccc(cc1)N1CCN(CCCCn2c3ccccc3n(-c3ccc(F)cc3)c2=O)CC1
Structure:
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