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TargetFatty acid-binding protein 4 (FABP4)
LigandBDBM312320
Substrate/Competitorn/a
Meas. Tech.Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay
IC50 20.0±n/a nM
Citation Buettelmann, BCeccarelli, SMKuehne, HKuhn, BNeidhart, WObst Sander, URichter, H Bicyclic thiophenylamide compounds US Patent US9604977 Publication Date 3/28/2017
More Info.:Get all data from this article,  Assay Method
 
Fatty acid-binding protein 4 (FABP4)
Name:Fatty acid-binding protein 4 (FABP4)
Synonyms:A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4
Type:Enzyme
Mol. Mass.:14719.23
Organism:Homo sapiens (Human)
Description:P15090
Residue:132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN
TEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVM
KGVTSTRVYERA
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  Blast E-value cutoff:
BDBM312320
NameBDBM312320
Synonyms:3-[3-(3-Isopropyl-[1,2,4]oxadiazol-5-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-bicyclo[2.2.2]oct-2-ene-2-carboxylic acid | US9604977, Example 68
TypeSmall organic molecule
Emp. Form.C23H27N3O4S
Mol. Mass.441.543
SMILESCC(C)c1noc(n1)-c1c(NC(=O)C2=C(C3CCC2CC3)C(O)=O)sc2CCCCc12 |t:14,(2.96,4.37,;1.47,4.77,;1.07,6.25,;.38,3.68,;-1.08,4.15,;-1.99,2.91,;-1.08,1.66,;.38,2.14,;-1.85,.33,;-.95,-.92,;.59,-.92,;1.36,-2.25,;.59,-3.59,;2.9,-2.25,;3.67,-3.59,;5.21,-3.59,;5.98,-2.25,;5.21,-.92,;3.67,-.92,;4.07,-2.41,;4.82,-2.1,;2.9,-4.92,;1.36,-4.92,;3.67,-6.25,;-1.85,-2.16,;-3.32,-1.69,;-4.65,-2.46,;-5.98,-1.69,;-5.98,-.15,;-4.65,.62,;-3.32,-.15,)|
Structure
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