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TargetFatty acid-binding protein 4 (FABP4)
LigandBDBM312344
Substrate/Competitorn/a
Meas. Tech.Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay
IC50 10.00±n/a nM
Citation Buettelmann, BCeccarelli, SMKuehne, HKuhn, BNeidhart, WObst Sander, URichter, H Bicyclic thiophenylamide compounds US Patent US9604977 Publication Date 3/28/2017
More Info.:Get all data from this article,  Assay Method
 
Fatty acid-binding protein 4 (FABP4)
Name:Fatty acid-binding protein 4 (FABP4)
Synonyms:A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4
Type:Enzyme
Mol. Mass.:14719.23
Organism:Homo sapiens (Human)
Description:P15090
Residue:132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN
TEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVM
KGVTSTRVYERA
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  Blast E-value cutoff:
BDBM312344
NameBDBM312344
Synonyms:2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,7-dihydro-5H-thieno[2,3-c]pyran-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid | US9604977, Example 90
TypeSmall organic molecule
Emp. Form.C19H17F3N2O4S2
Mol. Mass.458.474
SMILESOC(=O)C1=C(CCCC1)C(=O)Nc1sc2COCCc2c1-c1nc(cs1)C(F)(F)F |t:3|
Structure
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n/a