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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50374606
Substrate/Competitorn/a
Meas. Tech.Receptor Assay
Ki 5.22±1.11 nM
Citation McCurdy, CRMesangeau, CChin, FTJames, MLShen, BGambhir, SBiswal, SBehera, D Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders US Patent US9724435 Publication Date 8/8/2017  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma opioid receptor
Synonyms:Opioid receptor | Sigma | Sigma opioid receptor | Sigma-1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50374606
NameBDBM50374606
Synonyms:CHEMBL405925 | US9604926, Compound CM-124 | US9724435, Compound CM-124
TypeSmall organic molecule
Emp. Form.C20H29N3O2
Mol. Mass.343.4632
SMILESO=c1oc2ccccc2n1CCCN1CCN(CC1)C1CCCCC1
Structure
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