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Target
Vasopressin V1b receptor
Ligand
BDBM260249
Substrate
n/a
Meas. Tech.
Binding Test for V1b Receptor
pH
7.4±n/a
Temperature
298.15±n/a K
IC50
2.20±n/a nM
Comments
extracted
Citation
 Yoshinaga, M; Kuwada, T; Miyakoshi, N; Ishizaka, T; Wakasugi, D; Shirokawa, S; Hattori, N; Shimazaki, Y Azole derivative US Patent  US9522914 Publication Date 12/20/2016 
Target
Name:
Vasopressin V1b receptor
Synonyms:
AVPR V1b | AVPR V3 | AVPR1B | AVPR3 | Antidiuretic hormone receptor 1b | V1BR_HUMAN | V1bR | VASOPRESSIN V1B | VPR3 | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b) | Vasopressin V3 | Vasopressin V3 receptor
Type:
Enzyme
Mol. Mass.:
46985.01
Organism:
Homo sapiens (Human)
Description:
P47901
Residue:
424
Sequence:
MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAETIIF
  
Inhibitor
Name:
BDBM260249
Synonyms:
US9522914, B-02
Type:
Small organic molecule
Emp. Form.:
C25H30ClN5O2
Mol. Mass.:
467.991
SMILES:
CC(C)NC(=O)Cn1nc(nc1-c1cccc(Cl)c1)-c1ccc(CCN2CCOCC2)cc1
Structure:
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