Target

Ligand

Substrate

Meas. Tech.

Human A1 Adenosine Receptor Binding Assay

Ki

>10000±n/a nM

Citation

 Cosimelli, B; Greco, G; Ehlardo, M; Novellino, E; Da Settimo, F; Taliani, S; La Motta, C; Bellandi, M; Tuccinardi, T; Martinelli, A; Ciampi, O; Trincavelli, ML; Martini, C Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists. J Med Chem 51:1764-70 (2008) [PubMed]  Article Copy BDB DOI

More Info.:

Get all data from this article,   Solution Info,  Assay Method

Name:

Adenosine receptor A2a

Synonyms:

A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

44716.46

Organism:

Homo sapiens (Human)

Description:

P29274

Residue:

412

Sequence:

MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM21213

Synonyms:

2,2 -(4H-1,2,4-triazole-3,5-diyl)dipyridine | 2-[3-(2-pyridyl)-1H-1,2,4-triazol-5-yl]pyridine | 2-[5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]pyridine | CHEMBL260311 | triazole-dipyridine, A

Type:

Small organic molecule

Emp. Form.:

C12H9N5

Mol. Mass.:

223.2334

SMILES:

c1ccc(nc1)-c1nnc([nH]1)-c1ccccn1

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

BDBM21241

Synonyms:

Adenosine, N6-Ethyl-carboxamido | Adenosine-5 -(N-ethylcarboxamide) | N-Ethylcarboxamidoadenosine | [3H]NECA

Type:

n/a

Emp. Form.:

n/a

Mol. Mass.:

n/a

SMILES:

n/a

Structure: